Quality Engineer - CSV / GxP Manufacturing.Monday-Friday | 8:00 AM - 5:00 PM.Month Contract | Possible Extension / Temp-to-Perm.Quality professional with strong CSV, GxP, and manufacturing systems ...[show_more][last_updated.last_updated_variable_days]
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Davie, FL (Onsite) Monday-Friday | 8:00 AM - 5:00 PM 6-Month Contract | Possible Extension / Temp-to-Perm Sigma, Inc.
Sigma, Inc. is seeking a Quality Engineer to support computer system validation (CSV) and digital manufacturing systems at our onsite location in Davie, Florida. This role is ideal for a Quality professional with strong CSV, GxP, and manufacturing systems experience who thrives at the intersection of Quality, Engineering, and IT.
Key Responsibilities
Computer System Validation (CSV)
Review, approve, and maintain CSV lifecycle documentation including:
VMP, URS, FRS, HDS
Risk Assessments, IQ/OQ/PQ
RTM and Validation Summary Reports
Ensure risk-based validation approaches aligned with GAMP 5, 21 CFR Part 11, Annex 11, and ALCOA+ Data Integrity principles
Evaluate system changes through change control, assessing GxP impact and validation requirements
Support periodic reviews and re-validation of existing computerized systems
Digital Systems & Platforms
Act as Quality reviewer/approver for regulated systems including:
MES / EBR platforms (Werum Client-X or similar)
Process Historians (OSIsoft PI, PI Vision, or equivalent)
Advanced analytics tools (Seeq for GxP trending)
Empower and other laboratory systems
Review and approve system configurations related to:
Data acquisition and interfaces
Time stamping and audit trails
User access controls
Electronic records and electronic signatures
Segregation of GxP vs non-GxP analytics use cases
Data Integrity & Compliance
Assess and approve data flows, integrations, and interfaces
Support FDA, EMA, and internal audits related to computerized systems
Ensure continuous inspection readiness
Cross-Functional Collaboration
Partner with Engineering, Automation, MS&T, IT, and Operations
Provide Quality input during:
Project design
FAT / SAT
Commissioning and qualification phases
Enable efficient project execution while avoiding over-validation
Required Qualifications
Education
Master's degree in Engineering, Computer Science, Life Sciences, or related field (Recent graduates encouraged if experience requirements are met)
Experience
Minimum 3 years in pharmaceutical or regulated manufacturing
At least 2 years within a Quality organization
3+ years of hands-on CSV experience reviewing and approving validation documentation
Direct experience supporting manufacturing or utilities systems (not lab-only)
Technical Knowledge
CSV lifecycle & GAMP 5
21 CFR Part 11 / Annex 11
Data Integrity (ALCOA+)
Change control, deviations, and CAPA systems
MES / EBR, Process Historians, and GxP analytics platforms
Preferred / Nice-to-Have
Experience with:
Werum Client-X
Seeq
PI Vision
Power BI (regulated trending)
Agile or Lean validation approaches
C&Q integration with CSV
Participation in FDA inspections
Industry 4.0 or site digitalization initiatives
Key Competencies
Risk-based decision making with strong compliance focus
Excellent documentation review and technical writing skills
Ability to challenge constructively and offer solutions
Comfortable working across Quality, Engineering, and IT