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Makeup artist • sacramento ca
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Manager, Manufacturing Sciences & Technology (MSAT)
Orca BioSacramento, California, United States, 95811[job_card.variable_hours_ago]
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Manager, Manufacturing Sciences & Technology (MSAT)
$115,000 - $145,000 a year
Manager, Manufacturing Sciences & Technology (MSAT)
More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a late-stage biotechnology company redefining the transplant process by developing next-generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks. With our purified, high-precision investigational cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.
We have built a state-of-the-art, 100,000-square-foot manufacturing facility in Sacramento, CA (7910 Metro Air Pkwy) to ensure the consistent and reliable delivery of our high-precision cell therapy products. This site is essential to advancing our clinical pipeline and supporting future commercial availability of our life-saving therapies.
The Manager, Manufacturing Science and Technology (MSAT) is responsible for leading Manufacturing Science and Technology process engineers, across several shifts, within the commercial manufacturing site. This role oversees the day-to-day MSAT operations to support clinical and commercial production, deviations, product impact assessments, change controls, CAPAs, risk assessment, tech transfer and continuous improvement of manufacturing processes and technologies to ensure product quality, efficiency and compliance with regulatory standards.
Physical Demands
- Production Associate Roles: Must have visual acuity of 20/20 (corrected or uncorrected) and normal color vision to safely perform critical tasks such as visual inspection of materials, equipment, and labeling, including distinguishing color-coded components in a GMP environment.
- Must be able to meet cleanroom gowning requirements, including wearing full gowning (face coverings, gloves, hoods, goggles) for extended periods, as needed. Use of cosmetics (makeup, painted nails), jewelry, or facial piercings is not permitted in the cleanroom, and any skin conditions that cause shedding must be disclosed.
Work Conditions
- Must be able to work at either Orca Bio Sacramento location (3400 Business Dr. or 7910 Metro Air Pkwy) based on operational needs.
- Must be comfortable regularly participating in video-based meetings.
- May be required to work scheduled overtime, weekends, or holidays based on business needs.
Essential Duties & Key Responsibilities:
- Lead a small team of engineers and technical experts
- Provide leadership and guidance in technical decision-making related to manufacturing operations
- Manage review and approval of quality records owned or supported by MSAT
- Implement process improvements based on data analysis and scientific principles
- Lead efforts in production excellence to support commercial scalability and compliance
- Support the transfer of processes from R&D into GMP manufacturing facilities
- Collaborate with cross functional teams to trouble shoot and resolve technical issues
Minimum Qualifications:
- B.S. in Engineering, Chemistry, Pharmacy or related scientific discipline required
- 6+ years of industry experience with manufacturing processes and equipment in related fields: biologics, pharmaceutical fill and finish or drug substance manufacturing, Chemical or food industries
- 3+ years of people leadership experience
- Prior experience in regulated, GMP manufacturing operations
- Strong communication and problem-solving skills
Preferred Qualifications:
- Masters or PhD in Chemical Engineering, Biochemistry or Biology is preferred
- 2 to 4 years of leadership experience preferred
- Experience in Cell therapy manufacturing preferred
The anticipated annual salary range for this job is based on prior experience in the role/industry, education, location, internal equity, and other job-related factors as permitted by law. For remote-based positions, this range may vary based on your local market. You will also be eligible to receive pre-IPO equity, in addition to competitive medical, dental, and vision benefits, PTO, 401(k) plan, life and accidental death and disability coverage, and parental leave benefits. Other perks include subsidized daily lunches and snacks at our on-site locations.
Who we are
We are driven by a passion for science and compassion for patients. We act with urgency to ensure our treatments are one day accessible to all who need them.
We live by our core values of passion, courage, and integrity. Excellence in our work means the chance to unlock a better quality of life for our patients, and with that comes tremendous responsibility.
We innovate on a path that hasnt been paved. We embrace an entrepreneurial spirit and take calculated risks to achieve our mission. We arent afraid to ask why not and challenge the status quo.
We maintain a start-up culture of camaraderie and leadership by example, regardless of title.
Were proud to be an equal opportunity employer, and recognize that celebrating our differences creates stronger, lasting solutions that better serve our team, our patients and their healthcare providers.
Notice to staffing firms
Orca Bio does not accept resumes from staffing agencies with which we do not have a written agreement and specific engagement for a particular opening. Our employment activities, inquiries and offers are managed through our HR/Talent team, and all candidates are presented through this channel only. We do not accept unsolicited resumes, and we rarely outsource recruitment.
$115,000 - $145,000 a year
Compensation details: 115000-145000 Yearly Salary
PIb9b8ecd46628-30511-39942080