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Principal Scientist

Principal Scientist

Phlow Corp.Richmond, VA, US
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The Principal Chemist will possess an in-depth knowledge of process chemistry skills for the development of synthetic routes for drug substances. The candidate will perform multi-step chemical synth...serp_jobs.internal_linking.show_moreserp_jobs.last_updated.last_updated_30
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Principal Scientist

Principal Scientist

SolenisWilmington, DE, United States
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Solenis is a leading global producer of specialty chemicals focused on delivering sustainable solutions for water-intensive industries, including consumer, industrial, institutional, food and bever...serp_jobs.internal_linking.show_moreserp_jobs.last_updated.last_updated_30
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Principal Scientist

Principal Scientist

Galois, Inc.Boston, MA, US
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About Galois Who We Are : From building digital engineering tools that make space exploration safer to verifying cryptographic libraries that protect some of the world's most valuable data, Galoi...serp_jobs.internal_linking.show_moreserp_jobs.last_updated.last_updated_variable_days
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Principal Scientist

Principal Scientist

ExponentMenlo Park, California, USA
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Our vision is to engage multidisciplinary teams of science engineering and regulatory experts to empower clients with solutions that create a safer healthier more sustainable world.For over five de...serp_jobs.internal_linking.show_moreserp_jobs.last_updated.last_updated_variable_days
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Principal Scientist

Principal Scientist

Solenis LLCWilmington, DE, United States
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Solenis is a leading global producer of specialty chemicals focused on delivering sustainable solutions for water-intensive industries, including consumer, industrial, institutional, food and bever...serp_jobs.internal_linking.show_moreserp_jobs.last_updated.last_updated_30
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Principal Scientist

Principal Scientist

Steuben Foods Inc.Elma, NY, United States
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The Principal Scientist will serve as a technical leader and subject matter expert, driving R&D strategy across alternative protein platforms—including plant-based proteins, precision fermentation,...serp_jobs.internal_linking.show_moreserp_jobs.last_updated.last_updated_variable_days
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Principal Scientist

Principal Scientist

Adobe Inc.San Jose, CA, US
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Our Company Changing the world through digital experiences is what Adobe's all about.We give everyone— from emerging artists to global brands — everything they need to design and deliver exceptiona...serp_jobs.internal_linking.show_moreserp_jobs.last_updated.last_updated_variable_days
Principal Scientist

Principal Scientist

AustinPx Pharmaceutics and ManufacturingGeorgetown, TX, US
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Serve as technical lead for complex projects, guiding formulation and process development strategy from concept through commercialization. Define scientific direction for new programs and ...serp_jobs.internal_linking.show_moreserp_jobs.last_updated.last_updated_30
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Principal Scientist

Principal Scientist

Clinical Dynamix, Inc.Waltham, MA, US
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Principal Scientist (Contract to Perm); Hybrid in office 3 days per week.Reporting to the VP, Clinical Pharmacology, the Principal Scientist will work with Discovery Research and Development team m...serp_jobs.internal_linking.show_moreserp_jobs.last_updated.last_updated_variable_days
Principal Scientist

Principal Scientist

Certified GroupBurbank, CA, United States
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Certified Group partners with customers to deliver innovative scientific solutions and expertise - So The World Can Trust In What It Consumes™. As a leading provider of laboratory testing, regulator...serp_jobs.internal_linking.show_moreserp_jobs.last_updated.last_updated_1_day
Principal Scientist

Principal Scientist

Xaira TherapeuticsBrisbane, CA, United States
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Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development.The company is leading the development of generative AI models to design protein and anti...serp_jobs.internal_linking.show_moreserp_jobs.last_updated.last_updated_1_day
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Principal Scientist

Principal Scientist

Element Materials TechnologySt Paul, MN, United States
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Job Locations US-MN-Eagan ID 2025-17661 .Element has an opportunity for a.R&D and lot release for medical devi...serp_jobs.internal_linking.show_moreserp_jobs.last_updated.last_updated_variable_days
Principal Scientist

Principal Scientist

Food Safety Net ServicesBurbank, CA, United States
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Certified Group partners with customers to deliver innovative scientific solutions and expertise - So The World Can Trust In What It Consumes. As a leading provider of laboratory testing, regulatory...serp_jobs.internal_linking.show_moreserp_jobs.last_updated.last_updated_1_day
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Principal Scientist

Principal Scientist

AdobeSan Francisco, CA, US
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Our Company Changing the world through digital experiences is what Adobe's all about.We give everyone—from emerging artists to global brands—everything they need to design and deliver exceptional d...serp_jobs.internal_linking.show_moreserp_jobs.last_updated.last_updated_variable_days
Principal Scientist

Principal Scientist

Certified Laboratories IncBurbank, CA, US
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Certified Group partners with customers to deliver innovative scientific solutions and expertise – So The World Can Trust In What It Consumes™. As a leading provider of laboratory testin...serp_jobs.internal_linking.show_moreserp_jobs.last_updated.last_updated_30
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Principal Scientist

Principal Scientist

Clinical DynamixBoston, Massachusetts, United States
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This range is provided by Clinical Dynamix.Your actual pay will be based on your skills and experience — talk with your recruiter to learn more. Principal Scientist (Contract to Perm); Hybrid in off...serp_jobs.internal_linking.show_moreserp_jobs.last_updated.last_updated_variable_days
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Principal Scientist

Principal Scientist

Germer International - Pharmaceutical RecruitingWaterloo, IA, US
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Our pharmaceutical client is seeking a Principal Scientist who will be responsible for evaluating and interpreting analytical results, as well as developing, validating, and transferring analytical...serp_jobs.internal_linking.show_moreserp_jobs.last_updated.last_updated_30
Principal Scientist

Principal Scientist

Phlow CorpRichmond, VA, United States
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The Principal Chemist will possess an in-depth knowledge of process chemistry skills for the development of synthetic routes for drug substances. The candidate will perform multi-step chemical synth...serp_jobs.internal_linking.show_moreserp_jobs.last_updated.last_updated_30
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Principal Scientist

Principal Scientist

Gilead SciencesOceanside, California, USA
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At Gilead were creating a healthier world for all people.For more than 35 years weve tackled diseases such as HIV viral hepatitis COVID-19 and cancer working relentlessly to develop therapies that...serp_jobs.internal_linking.show_moreserp_jobs.last_updated.last_updated_variable_days
Principal Scientist

Principal Scientist

Phlow Corp.Richmond, VA, US
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Job Description

Job Description

Description :

The Principal Chemist will possess an in-depth knowledge of process chemistry skills for the development of synthetic routes for drug substances. The candidate will perform multi-step chemical syntheses and product isolation / purification operations in the laboratory either independently or as part of a project team. The candidate will ensure excellence of our process development and technical transfer to Phlow’s partners or customers. The candidate will personify Phlow’s shared values and culture, both internally and externally. The candidate will work with the highest standards of safety, integrity, transparency, and ethics to create win-win scenarios for patients, customers, and partners.

Responsibilities :

  • Provide process chemistry support to Phlow’s Continuous Manufacturing R&D lab to ensure the deliverables to customer’s projects are met on time and on budget.
  • Independently design, synthesize, purify, and analyze chemical intermediates, target compounds, and impurities.
  • Maintain accurate, legible, and complete records of all experiments and observations.
  • Author progress reports and present scientific results to team members.
  • Exhibit a high level of safety awareness and conduct lab operations in a safe manner.
  • Contribute to the timely and accurate preparation of regulatory submissions.
  • Participate in the ongoing continuous improvements in manufacturing processes resulting in improving product quality, robustness, and cost.
  • Collaborate with Analytical Chemistry, EH&S, Engineering, Project Management, Quality Assurance and Regulatory Affairs to ensure strong working relationships with all partners and Phlow employees.

Requirements :

Preferred Qualifications :

  • Ph.D. with a minimum 3 years of experience, M.S with a minimum 7 years of experience, or B.S. degree with a minimum 10 years of experience in Organic Chemistry, Pharmaceutical Sciences, or a related scientific field.
  • Process chemistry and API manufacturing experience on multi-kilogram scale.
  • Knowledge of ICH and cGMP requirements.
  • Experience working for a contract organization (CROs / CMOs / CDMOs) is a plus.
  • Experience with technical and operational risk assessments (e.g., process robustness, mutagenic impurities, nitrosamines, etc.) is a plus.
  • Experience with design of experiments (DOE) and related multivariate experimentation approaches is a plus.
  • Experience with the development and implementation of continuous flow manufacturing processes is a plus.
  • Physical Requirements

  • Constantly required to see to utilize computer screens and monitors to perform job duties including reading & writing, as well as when presenting information and communicating with others.
  • Frequently required to talk or hear to communicate with employees, candidates, vendors, and others, including presenting information in front of groups.
  • Frequently required to reach with arms and hands performing repetitive motions and using finger dexterity to work primarily at a computer keyboard and with a mouse.
  • Frequently required to sit, and occasionally required to stand or walk to move around primarily in an office environment.
  • Occasionally lift and / or move up to 10 pounds.
  • To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed are representative of the knowledge, skill, and / or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.