Chief of Staff to the CDIO (Chief Digital & Information Officer)

Chief of Staff to the CDIO (Chief Digital & Information Officer)

Vertex Pharmaceuticals is seeking an experienced and driven Technology focused Chief of Staff to support our Chief Digital and Information Officer in leading Vertex’s digital transformation and IT strategy. This high‑impact role functions as a trusted advisor and operational leader for the Office of the CDIO, ensuring that Digital, Data, and Technology initiatives are executed with excellence and aligned with our mission to improve patients’ lives.

You will drive strategic planning, oversee key initiatives, enhance operational processes, and facilitate cross‑functional collaboration. The ideal candidate is a proactive problem‑solver with a strong background in digital and technology leadership and exceptional interpersonal skills.

Key Duties And Responsibilities

• Partner with the CDIO to develop and monitor strategic plans, OKRs, and roadmaps.
• Organize annual and quarterly planning processes for the CDIO organization, ensuring initiatives align with Vertex’s corporate strategy and budget.
• Lead and / or monitor execution of strategic projects and prepare progress reports and readouts for the CDIO and executive team.
• Support the CDIO in preparing for key meetings and decisions.
• Help manage the CDIO’s priorities by filtering incoming requests and focusing their attention on the most critical issues.
• Conduct research and data analysis on technology trends, operational performance, and new opportunities to inform the CDIO’s strategy.
• Develop high‑quality presentations, briefing documents, and updates for Executive Committee review, Board discussions, town halls, and other meetings.
• Support operationalization of the CDIO organization’s strategic plans, including proactive design and development of processes to enable the CDIO’s leadership team to achieve their objectives.
• This may include managing leadership team meetings, agendas, goal setting and reviews, metrics, and team activities.
• Identify and implement process improvements to optimize the efficiency of the CDIO’s organization.
• Facilitate effective communication between the CDIO and other Vertex leaders, as well as within the CDIO’s global team.
• This includes drafting organizational messages and developing a communications strategy to effectively share updates across the function.
• Drive ad‑hoc strategic projects as identified by the CDIO.

Knowledge And Skills

Education And Experience

Pay Range

$182,800 - $274,200

Disclosure Statement

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job‑related factors permitted by law.

Benefits and Flex Designation

Vertex offers inclusive market‑leading benefits, including medical, dental, and vision benefits, generous paid time off, educational assistance, a generous commuting subsidy, charitable donation matching, 401(k), and more.

Flex Designation

Hybrid‑Eligible or On‑Site Eligible. In this Hybrid‑Eligible role, you can choose to be designated as :

Note : The Flex status for this position is subject to Vertex’s policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation. We are committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E‑Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and / or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com.

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