Talent.com
Director of AI Enterprise Architecture (Boston)
Director of AI Enterprise Architecture (Boston)Maitsys • Boston, MA, US
[error_messages.no_longer_accepting]
Director of AI Enterprise Architecture (Boston)

Director of AI Enterprise Architecture (Boston)

Maitsys • Boston, MA, US
[job_card.variable_days_ago]
[job_preview.job_type]
  • [job_card.full_time]
  • [job_card.part_time]
[job_card.job_description]

Job Description : Director, AI Enterprise Architecture (GxP / GMP Pharma Manufacturing)

Location : Boston, MA (Hybrid)

Company : Maitsys Inc.

Experience : 10+ years (1215+ preferred)

Type : Full-time, Leadership Role

About the Role

Maitsys Inc. is seeking a visionary Director of AI Enterprise Architecture to lead the design, strategy, and implementation of next-generation AI solutions for our pharmaceutical and biotech manufacturing clients. This senior leader will define enterprise-wide AI architecture, drive GxP / GMP-compliant AI innovation, and serve as a trusted advisor to client executives and business leaders.

The Director will play a central role in shaping Maitsyss AI strategy and will directly influence how our clients adopt GenAI, agentic AI, intelligent automation, and data-driven decision systemsensuring alignment with regulated industry standards and business outcomes.

This position requires a unique mix of strategic leadership, architectural depth, GxP domain expertise, and strong client-facing consulting ability.

Key Responsibilities

AI Strategy, Vision & Leadership

  • Define and lead the overall AI enterprise architecture vision for Maitsys and its clients.
  • Develop multi-year AI roadmaps, strategic frameworks, and adoption models for pharma manufacturing organizations.
  • Lead executive-level AI discussions, articulating business value, risk management, and transformation opportunities.
  • Drive responsible, ethical, and secure AI adoption aligned to regulatory compliance.

Enterprise Architecture & Technical Oversight

  • Architect end-to-end solutions leveraging GenAI, agentic AI, LLM platforms, RAG systems, vector databases, MLOps, and cloud services.
  • Build and maintain AI architecture standards, blueprints, design patterns, and reusable frameworks.
  • Direct solution architecture reviews and ensure systems meet GxP / GMP, data integrity (ALCOA+), 21 CFR Part 11, and Annex 11 requirements.
  • Oversee complex AI platform integrations across MES, QMS, LIMS, ELN, SCADA, ERP and manufacturing data systems.

    • Business Advisory & Process Optimization

  • Engage with business stakeholdersmanufacturing, QA / QC, supply chain, labsto identify high-impact AI transformation opportunities.
  • Translate business processes into AI-enabled workflows and automation strategies.
  • Facilitate workshops and design sessions to accelerate clients AI readiness and workforce enablement.
  • Serve as a thought partner for C-level and VP-level decision makers.

    • Technical Translation & Delivery Support

  • Convert business needs into detailed technical requirements for AI engineers, data engineers, and ML teams.
  • Provide leadership throughout model ideation, development, testing, validation, and deployment.
  • Ensure models follow best practices for performance, reliability, explainability, and compliance.
  • Oversee implementation of AI agents, copilots, knowledge assistants, and domain-specific automation solutions.

    • Compliance, Governance & Data Integrity

  • Design AI systems that comply with :
  • GMP / GxP
  • 21 CFR Part 11
  • EU Annex 11
  • CSV / CSA guidelines
  • ALCOA+ data integrity principles
  • Partner with validation, QA, security, and compliance teams to ensure proper documentation and controls.

    • Practice Leadership & Growth

  • Build and mentor a high-performing AI architecture team within Maitsys.
  • Contribute to thought leadership, playbooks, accelerators, and delivery methodologies.
  • Support pre-sales, proposals, SOW creation, and client advisory engagements.
  • Represent Maitsys at conferences, industry events, and client innovation forums.

    • Required Qualifications

  • 1215+ years of experience in Pharma, Biotech, Life Sciences, or regulated manufacturing.
  • Extensive background in GxP / GMP, CSV / CSA, quality systems, and compliance frameworks.
  • Deep expertise in enterprise architecture for AI / ML, GenAI, agentic systems, and cloud environments.
  • Hands-on experience with :
  • OpenAI, Azure OpenAI, Anthropic, or similar LLM platforms
  • RAG architectures, prompt engineering, vector databases
  • AWS, Azure, or GCP
  • MLOps, model governance, and monitoring
  • Proven ability to lead client-facing architecture discussions and influence senior executives.
  • Strong communication and storytelling skills with both technical and non-technical audiences.
  • Experience leading cross-functional AI delivery teams.

    • Preferred Qualifications

  • Experience with GAMP 5, AI validation frameworks, and regulated system integration.
  • Familiarity with MES (Werum / Siemens), LIMS (LabWare / STARLIMS), QMS (TrackWise / Veeva), or manufacturing data lakes.
  • Prior leadership role in consulting, digital transformation, or enterprise architecture.
  • MBA, M.S. in AI / ML / Data Science, or TOGAF certification is a plus (not required).

    • Why Join Maitsys?

  • Influence the AI vision and digital transformation of global pharmaceutical manufacturers.
  • Lead high-impact, cutting-edge GenAI initiatives.
  • Work with a rapidly growing team in a leadership role.
  • Opportunity to build Maitsyss AI architecture practice from the ground up.
  • Collaborative culture with strong executive support.
    • [job_alerts.create_a_job]

    Director Enterprise Architecture • Boston, MA, US

    [internal_linking.similar_jobs]
    Director - Technology - AI / Robotics

    Director - Technology - AI / Robotics

    Boston Staffing • Boston, MA, US
    [job_card.full_time]
    Director - Technology - AI / Robotics.We are seeking a Director - Technology - AI / Robotics to lead the exploration, evaluation, and application of emerging technologies in artificial intelligence and...[show_more]
    [last_updated.last_updated_variable_hours] • [promoted] • [new]
    AI Architecture, Senior Director

    AI Architecture, Senior Director

    Point Wild (Formerly Pango Group) • Boston, MA, United States
    [job_card.full_time]
    Point Wild (formerly Pango Group) is building Lat 61, a platform that ingests, normalizes, and enriches diverse data sources to power AI agents, analytics, and decision-making systems.As AI Archite...[show_more]
    [last_updated.last_updated_30] • [promoted]
    Director of Engineering — Build & Scale AI SaaS

    Director of Engineering — Build & Scale AI SaaS

    Passive • Boston, MA, United States
    [job_card.full_time]
    A leading tech company in Boston is seeking a Director of Engineering to lead the engineering function across mobile, backend, and AI. The ideal candidate will have over 7 years of experience in eng...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    AI-Driven Enterprise Growth Director

    AI-Driven Enterprise Growth Director

    Tomorrow Companies Inc. • Boston, MA, United States
    [job_card.full_time]
    A leading technology company in Boston is seeking an AI Director of Enterprise Growth.This hands-on role involves shaping high-quality pipeline growth through digital campaigns, website optimizatio...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Director of Engineering — AI-Driven, Scalable Platforms

    Director of Engineering — AI-Driven, Scalable Platforms

    Barracuda • Boston, MA, United States
    [job_card.full_time]
    A leading cybersecurity company based in Boston is seeking a Director of Engineering to lead diverse teams through transformation and growth while driving excellence in software development practic...[show_more]
    [last_updated.last_updated_variable_hours] • [promoted] • [new]
    Senior Director, Cloud Platform & AI Innovation

    Senior Director, Cloud Platform & AI Innovation

    Ll Oefentherapie • Boston, MA, United States
    [job_card.full_time]
    A leading tech firm in Boston is seeking a seasoned product leader for Oracle Integration Cloud.The ideal candidate will have over 10 years of experience in enterprise technology and cloud data pla...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Director, AI Engineering — Lead Scalable Agentic AI Systems

    Director, AI Engineering — Lead Scalable Agentic AI Systems

    Blue Cross Blue Shield of Massachusetts • Boston, MA, United States
    [job_card.full_time]
    A leading healthcare provider is seeking a Sr.Manager, AI Engineering to lead the development of advanced AI systems.This role involves establishing a strategic vision, designing scalable AI archit...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Director of Architecture — FinTech Solutions, Hybrid

    Director of Architecture — FinTech Solutions, Hybrid

    Soteria Reinsurance Ltd. • Boston, MA, United States
    [job_card.full_time]
    A leading financial services company located in Boston, MA is looking for a Technical Solution Architect to define technical architectures and work closely with business and technology leaders.The ...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Director, AI Solutions — Growth & Partnerships

    Director, AI Solutions — Growth & Partnerships

    TransPerfect • Boston, MA, United States
    [job_card.full_time]
    A global leader in language solutions is seeking a Director of Business Development for AI Solutions in Boston.This role requires strong B2B sales experience, with a focus on cultivating strategic ...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Enterprise Architect

    Enterprise Architect

    Contact Government Services, LLC • Boston, MA, US
    [job_card.full_time]
    Employment Type : Full-Time, Senior-Level.Department : Information Technology.CGS is seeking an experienced senior-level Information Technology Enterprise Architect to support the I.The ideal applica...[show_more]
    [last_updated.last_updated_30] • [promoted]
    Sr. Director, AI Enablement

    Sr. Director, AI Enablement

    Zelis Healthcare, LLC • Boston, MA, United States
    [job_card.full_time]
    Zelis is modernizing the healthcare financial experience across payers, providers, and healthcare consumers.We serve more than 750 payers, including the top five national health plans, regional hea...[show_more]
    [last_updated.last_updated_30] • [promoted]
    Director of Enterprise Sales

    Director of Enterprise Sales

    Dandelion Energy • Boston, MA, US
    [job_card.full_time]
    Dandelion Energy is transforming how homes are heated and cooled—starting from (below) the ground up.As the nation's leading residential geothermal company, we design, install, and mainta...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Director of Engineering Operations

    Director of Engineering Operations

    Whoop • Boston, MA, US
    [job_card.full_time]
    At WHOOP, we’re on a mission to unlock human performance and healthspan.WHOOP empowers members to understand their bodies through continuous measurement of physiological data, enabling them t...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Director - Enterprise Architecture

    Director - Enterprise Architecture

    Houghton Mifflin Harcourt Co • Boston, MA, United States
    [job_card.full_time]
    Press Tab to Move to Skip to Content Link.Select how often (in days) to receive an alert : Create Alert.Houghton Mifflin Harcourt is a global learning company with the mission of changing people's.A...[show_more]
    [last_updated.last_updated_30] • [promoted]
    Principal Data Engineer - AI Architect

    Principal Data Engineer - AI Architect

    American Family Insurance • Boston, MA, United States
    [job_card.full_time]
    As the Principal Data Engineer - AI Architect you will lead the architectural design (conceptual, logical and physical) of large-scale AI business solutions. As a technical lead, you will guide and ...[show_more]
    [last_updated.last_updated_30] • [promoted]
    Senior Director, AI and Analytics

    Senior Director, AI and Analytics

    Alnylam Pharmaceuticals • Cambridge, MA, United States
    [job_card.full_time]
    This role is considered [[custWorkplaceType.We are seeking a Senior Director, AI and Analytics with a passion for architecting solutions, building systems, and delivering real business impact throu...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Senior Director, Software Engineering

    Senior Director, Software Engineering

    Pickle Robot Company • Charlestown, MA, US
    [job_card.full_time]
    Pickle is on the hunt for a dynamic and driven Senior Director of Software Engineering to revolutionize the future of warehouse automation. The ideal candidate is an experienced engineering leader w...[show_more]
    [last_updated.last_updated_30] • [promoted]
    Director of AI & Data Services Pharma Background Full Time

    Director of AI & Data Services Pharma Background Full Time

    Chabez Tech • Boston, MA, US
    [job_card.full_time]
    Senior Account Director – Pharma (Data & AI Services).We are seeking an experienced .Senior Account Director with a strong pharma background and expertise in Big Data and Data Analyt...[show_more]
    [last_updated.last_updated_30] • [promoted]