Talent.com
Senior Research Scientist, Biophysics (South San Francisco)
Senior Research Scientist, Biophysics (South San Francisco)Yoh, A Day & Zimmermann Company • South San Francisco, CA, United States
Senior Research Scientist, Biophysics (South San Francisco)

Senior Research Scientist, Biophysics (South San Francisco)

Yoh, A Day & Zimmermann Company • South San Francisco, CA, United States
[job_card.variable_days_ago]
[job_preview.job_type]
  • [job_card.full_time]
[job_card.job_description]

Yoh is looking for a skilled and driven Senior Research Scientist, Biophysics with hands-on experience in small molecule drug discovery to join our collaborativeLead Discoveryteam. This is a lab-based role focused on the biophysical and mechanistic characterization of small molecule-protein interactions to support our drug discovery pipeline. This candidate must have hands on experience with designing and executing binding characterization studies using SPR.

Industry : Discovery and Development

Location : South San Francisco, CA

Key Responsibilities :

  • Design and execute binding characterization studies using SPR (Biacore S200 and 8K+).
  • Conduct routine compound screening and mechanistic studies using biophysical assays (e.g., nanoDSF, DLS, Spectral Shift).
  • Manage and coordinate outsourced biophysical studies with CROs.
  • Analyze and interpret data to support SAR and lead optimization across multiple projects.
  • Maintain detailed experimental records and present findings in internal meetings and reports.

Qualifications :

  • PhD in Biophysics, Biochemistry, or a related field.
  • Minimum 3 years of relevant industry experience in small molecule drug discovery biophysics.
  • Proven expertise in SPR assay development and data interpretation.
  • Demonstrated expertise in designing, developing, and interpreting biophysical characterization of small molecule-protein interactions by SPR.
  • Strong familiarity with additional biophysical techniques (TSA, DLS, Spectral Shift, NMR, ITC, etc.).
  • Proficiency with data analysis and graphing tools is a plus.
  • #IND-SPG

    Estimated Min Rate : $70.00

    Estimated Max Rate : $80.00

    Whats In It for You?

    We welcome you to be a part of the largest and legendary global staffing companies to meet your career aspirations. Yohs network of client companies has been employing professionals like you for over 65 years in the U.S., UK and Canada. Join Yohs extensive talent community that will provide you with access to Yohs vast network of opportunities and gain access to this exclusive opportunity available to you. Benefit eligibility is in accordance with applicable laws and client requirements. Benefits include :

  • Medical, Prescription, Dental & Vision Benefits (for employees working 20+ hours per week)
  • Health Savings Account (HSA) (for employees working 20+ hours per week)
  • Life & Disability Insurance (for employees working 20+ hours per week)
  • MetLife Voluntary Benefits
  • Employee Assistance Program (EAP)
  • 401K Retirement Savings Plan
  • Direct Deposit & weekly epayroll
  • Referral Bonus Programs
  • Certification and training opportunities
  • Note : Any pay ranges displayed are estimations. Actual pay is determined by an applicant's experience, technical expertise, and other qualifications as listed in the job description. All qualified applicants are welcome to apply.

    Yoh, a Day & Zimmermann company, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

    Visit https : / / www.yoh.com / applicants-with-disabilities to contact us if you are an individual with a disability and require accommodation in the application process.

    For California applicants, qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. All of the material job duties described in this posting are job duties for which a criminal history may have a direct, adverse, and negative relationship potentially resulting in the withdrawal of a conditional offer of employment.

    It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

    By applying and submitting your resume, you authorize Yoh to review and reformat your resume to meet Yohs hiring clients preferences. To learn more about Yohs privacy practices, please see our Candidate Privacy Notice : https : / / www.yoh.com / privacy-notice

    [job_alerts.create_a_job]

    Senior Research Scientist • South San Francisco, CA, United States

    [internal_linking.related_jobs]
    Senior GenAI Research Scientist Scaling

    Senior GenAI Research Scientist Scaling

    Databricks • San Francisco, California, USA
    [job_card.full_time]
    At Databricks we are obsessed with enabling data teams to solve the worlds toughest problems from security threat detection to cancer drug development. We do this by building and running the worlds ...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Senior Research Scientist (LLMs)

    Senior Research Scientist (LLMs)

    Aldea Inc • San Francisco, California, United States, 94102
    [job_card.full_time]
    Aldea is a multi-modal foundational AI company reimagining the scaling laws of intelligence.We believe today's architectures create unnecessary bottlenecks for the evolution of software.Our mission...[show_more]
    [last_updated.last_updated_30]
    Senior RL Research Scientist (San Francisco)

    Senior RL Research Scientist (San Francisco)

    DeepRec.ai • San Francisco, CA, US
    [job_card.part_time]
    Senior RL Research Scientist / Reinforcement Learning Scientist.Join a frontier AI team building systems that can act in the physical world, experimenting, optimizing, and controlling real processe...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Senior AI Benchmark Research Scientist

    Senior AI Benchmark Research Scientist

    Monarch Recruiters • San Francisco, CA, United States
    [job_card.full_time]
    A leading tech recruitment firm is seeking exceptional researchers and research engineers in San Francisco to lead the design and development of novel benchmarks for AI evaluation.This role demands...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Research Scientist (San Francisco Bay Area)

    Research Scientist (San Francisco Bay Area)

    Goliath Partners • San Francisco Bay Area, US
    [job_card.part_time]
    We're working with a San Francisco client that's got a research team of 50~ professionals and looking to further expand it. They are specifically looking to flesh out their Research Group by hiring ...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    AI-Driven Life Sciences Research Scientist

    AI-Driven Life Sciences Research Scientist

    anthropic • San Francisco, CA, United States
    [job_card.full_time]
    A leading AI research company in San Francisco is seeking a Research Scientist for its Life Sciences team.This position blends AI with biological research to drive scientific discovery.Ideal candid...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Senior GenAI Research Scientist - Scaling

    Senior GenAI Research Scientist - Scaling

    Menlo Ventures • San Francisco, CA, United States
    [job_card.full_time]
    At Databricks, we are obsessed with enabling data teams to solve the world’s toughest problems, from security threat detection to cancer drug development. We do this by building and running the worl...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Senior Research Associate / Scientist I, Protein Sciences

    Senior Research Associate / Scientist I, Protein Sciences

    ImmunEdge, Inc • Redwood City, CA, US
    [job_card.full_time]
    [filters_job_card.quick_apply]
    ImmunEdge is a biopharmaceutical company committed to developing novel therapeutics for patients with serious or life-threatening diseases. With a highly experienced team of experts in immunology an...[show_more]
    [last_updated.last_updated_30]
    Senior Scientist II, DMPK

    Senior Scientist II, DMPK

    Exelixis • Alameda, CA, United States
    [job_card.full_time]
    The Senior Scientist II, DMPK works with a fast-paced team in drug discovery research to provide scientific direction and strategy to find a potential safe and effective human dose through the desi...[show_more]
    [last_updated.last_updated_30] • [promoted]
    Senior AI Research Scientist New San Francisco, California

    Senior AI Research Scientist New San Francisco, California

    Workato Inc • San Francisco, CA, United States
    [job_card.full_time]
    Workato transforms technology complexity into business opportunity.As the leader in enterprise orchestration, Workato helps businesses globally streamline operations by connecting data, processes, ...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Senior GenAI Research Scientist - Scaling

    Senior GenAI Research Scientist - Scaling

    Databricks Inc. • San Francisco, CA, United States
    [job_card.full_time]
    At Databricks, we are obsessed with enabling data teams to solve the world’s toughest problems, from security threat detection to cancer drug development. We do this by building and running the worl...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Senior Scientist I, Drug Product and Device Development

    Senior Scientist I, Drug Product and Device Development

    Vir Biotechnology, Inc. • San Francisco, CA, United States
    [job_card.full_time]
    Senior Scientist I, Drug Product and Device Development.We believe the success of our colleagues drives the success of our mission. We are committed to creating a company where everyone feels suppor...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Research Scientist (San Francisco Bay Area)

    Research Scientist (San Francisco Bay Area)

    kadence • San Francisco Bay Area, CA, United States
    [job_card.full_time]
    We are a seed-stage AI company building the industry standard for evaluating and benchmarking large language models on real enterprise tasks. As a Research Scientist, you will develop new benchmarks...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Senior / Staff Research Scientist

    Senior / Staff Research Scientist

    Snorkel AI • San Francisco, CA, United States
    [job_card.full_time]
    Employer Industry : Artificial Intelligence Solutions.Why consider this job opportunity : .Opportunity for career advancement and growth within a rapidly scaling organization.Flexibility to work remot...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Senior Research Scientist

    Senior Research Scientist

    Heartflow • San Francisco, CA, United States
    [job_card.full_time]
    Heartflow is a medical technology company advancing the diagnosis and management of coronary artery disease, the #1 cause of death worldwide, using cutting-edge technology.The flagship product—an A...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Senior Research Scientist (LLMs)

    Senior Research Scientist (LLMs)

    Aldea • San Francisco, CA, United States
    [job_card.full_time]
    Headquartered in Miami, Aldea is a next‑generation AI company focused on voice‑based clinical and expert applications.Our flagship product, Advisor, uses proprietary AI to scale the impact of world...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Senior Research Scientist, Mechanistic Interpretability

    Senior Research Scientist, Mechanistic Interpretability

    Anthropic • San Francisco, CA, United States
    [job_card.full_time]
    A leading research-focused AI firm in San Francisco is seeking a Research Scientist specialized in Interpretability.This role involves developing methods to understand large language models through...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    research scientist - RL (San Francisco Bay Area)

    research scientist - RL (San Francisco Bay Area)

    Cerebro • San Francisco Bay Area, CA, United States
    [job_card.full_time]
    Join a Leading Applied Research Lab Pushing the Boundaries of Reinforcement Learning.Are you passionate about advancing the frontiers of. Develop novel optimization-based methods.Drive your own rese...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]