Director, Global Market Access

## Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose : leading the fight against MASH.

• Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).
• Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.
• Role Overview :
• Director, Global Market Access
• The Director, Global Market Access, is responsible for developing and supporting integrated global market access strategies that optimize pricing, recommendations, and payer acceptance for Madrigal’s product offering worldwide. Reporting to the Executive Director of Market Access, the Director collaborates with the Regional Market Access Lead(s) and across functions, ensuring alignment with business priorities and the effective positioning of Madrigal products. This is a hybrid position (3 days in office) is based in Waltham or Conshohocken.
• Position Responsibilities :
• Develop and Support Market Access Strategies
• Design and implement integrated global market access and payer strategies and approval processes with a deep understanding of payer dynamics and market access stakeholders, in collaboration with Regional Market Access Team(s)
• Align strategies with lifecycle management to optimize pricing, access, and funding for Madrigal products
• Lead payer market research, integrating product’s value proposition and supporting clinical information, to determine achievable price, including gross to net, and optimal evidence package
• Conduct secondary research for relevant analogues determining prices, HTA review outcomes, and burden of disease to inform price and market access estimates, inform target product profile and clinical trials development program
• Drive Market Access Potential
• Inform internal decision-making on portfolio prioritization, Target Product Profiles, and Target Value Propositions.
• Support strategies with deep functional knowledge, in-depth market research, robust data & analog assessments.
• Evaluate and mitigate corporate risk related to market access by monitoring environmental trends and emerging challenges, including P&R system reforms and evolving competitive access landscapes
• Foster Cross-Functional Collaboration
• Partner with HEOR to ensure robust value proposition and integrated evidence plans are optimized to support global market access and reimbursement
• Ensure global market access is aligned to the global brand strategy and build strong cross-functional relationships including : Marketing, Public Affairs, Communications, Medical Affairs, Regional Leads, and Country Market Access Leads
• Provide seamless rollout and training on global strategies, tools, and tactics across Regional and Country teams
• Qualifications :
• Bachelor’s degree required; advanced degree in healthcare or business preferred
• 12+ years of experience in biopharma with 6+ years in Global Market Access, experience directly in International markets preferred
• Proven ability to identify trends impacting business and develop strategies for sustainable success
• Experience in creating strategies for timely, quality, and affordable patient access
• Key competencies : quantitative and analytical skills driving towards strategic business solutions, financial acumen, strong written and oral communication skills including the ability to effectively write and deliver presentations to all levels
• Recognized as a team player with excellent interpersonal skills with experience navigating internal processes and mobilizing stakeholders in a collaborative, reliable manner
• Ability to influence and interface internally and externally at senior levels
• Experience navigating internal processes and mobilizing stakeholders
• Dynamic, enthusiastic, decisive, and self-motivated; possesses a sense of urgency with the ability and strong desire to "get things done”
• Domestic and International travel anticipated to be up to 30% between Madrigal HQ and other meetings as appropriateMadrigal offers a competitive Total Rewards strategy to attract and retain top talent and is inclusive of base pay, bonus, equity, and a generous benefits package. Full-time employees are eligible for base salary, bonus, equity, and a comprehensive benefits suite.Base salary is determined by several factors including the candidate’s qualifications, skills, education, experience, business needs, and market demands. As of the date of this posting, a good faith estimate of the current pay scale for this position, applicable to all candidates, is $223,000 - $273,000 per year. We comply with all applicable minimum wage laws.## All full-time employees receive equity, which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.## ## Full-time employees are also eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision and life / disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance, legal services, and other offerings. In addition, we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal, state, and local laws.## ## We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact HR@madrigalpharma.com.## ## Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law.## ## Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established.## ## Applications are being accepted on an ongoing basis and can be submitted through our site.## ##
• Please be aware that we have received reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals’ Hiring Managers, seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigal’s name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype, RingCentral or solely via telephone; charge candidates

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