Proposal Strategy and Operations Manager San Francisco, Remote

Proposal Strategy and Operations Manager

At PicnicHealth , we're building the future of non-interventional clinical research, powered by AI and centered on patients. Our mission is to make it radically easier, faster, and more affordable to generate high-quality real-world evidence. We're replacing the legacy, services-heavy model with a modern, AI-first approach that unlocks insights from rich, multi-modal data—from clinical notes and imaging to lab results—at scale. By engaging patients directly through our personal health assistant , PicnicAI, which meets them where they’re at and delights them along the way (with an industry leading NPS of 76), patients participate actively in the research they care about.

PicnicHealth is already a trusted partner to 7 of the top 10 pharmaceutical companies. Our work spans 40+ disease areas and has supported over 60 peer-reviewed publications, including an FDA submission that incorporates PicnicHealth data.

Founded in 2014, we’ve raised $100M+ from top investors like Amplify Partners, Felicis Ventures, B Capital Group, and Y Combinator. Our business running non-interventional studies more than doubled last year, and we’re growing even faster in 2025. We’re a team of doctors, patients, data nerds, engineers, and builders, reimagining how clinical research works — and we’re just getting started!

The Opportunity

As the Proposal Strategy and Operations Manager, you will build a system and process that enables a cross-functional team to transform complex technical capabilities into compelling, winning proposals . This role is critical to our success in the competitive non interventional study space requiring someone who can transform complex technical capabilities into compelling, winning proposals. This is a builder role. You’ll wear multiple hats—leading proposals, creating structure where it doesn’t exist, and partnering across teams. You won’t be doing this alone, but you will be accountable for making it happen.

At PicnicHealth, AI is at the core of everything we do. We're looking for individuals who are not just comfortable with, but genuinely excited by and actively experimenting with, the power and potential of AI.

What you’ll do :

• Strategic Proposal Leadership
• Develop and execute proposal strategies that differentiate PicnicHealth in competitive landscapes
• Collaborate with Sales, Scientific Solutions, Product Delivery and Operations teams to craft compelling value propositions
• Analyze RFPs and client requirements to develop winning positioning and messaging
• Proposal Management & Execution
• Leverage project management tools and processes to project manage complex, multi-stakeholder proposal processes with tight deadlines
• Coordinate cross-functional teams including Scientific Solutions, Product, Delivery and Operations, Legal, and Finance
• Ensure all proposals meet client requirements, compliance standards, and internal quality benchmarks
• Develop standardized templates, timelines, processes, and best practices to improve efficiency and win rates
• Identify, test and roll out technology and tools to build scalable processes that enable faster and more efficient proposals.
• Content Development & Optimization
• Levarge PicnicHealth experts to create compelling executive summaries, technical approaches, and capability statements
• Maintain and continuously improve proposal content library and knowledge management systems leveraging process, technology and tools
• Work with solutions and design to ensure consistent messaging and branding across all proposal materials
• Win / Loss Analysis & Continuous Improvement
• Conduct thorough win / loss analyses to identify improvement opportunities
• Track proposal metrics and conversion rates to optimize processes
• Collaborate with Sales teams to understand client feedback and market dynamics
• Implement process improvements based on data-driven insights

What you’ll bring :

$1M)

We expect all team members to be amazing in their roles and, ultimately, to move the PicnicHealth mission forward.

Why will PicnicHealth win in Clinical Research?

Trials are a major bottleneck in drug development, and the promising advancements in biotech cannot achieve their full potential unless clinical research becomes more effective. The industry runs on outdated technology and manual processes. Research sites (hospitals, academic centers, doctors' offices) are a major bottleneck, and contract research organizations (CROs) spend most of their time wrangling sites and cobbling together vendor software.

PicnicHealth has built technology that uniquely positions us to run faster, cheaper, and more flexible studies without requiring sites :

At PicnicHealth you get to solve real problems with real solutions, great tech, and great people. We look to attract and retain exceptional performers through a mission that matters, a culture that allows team members to do their best work and be their real selves, and through competitive compensation and benefits packages aligned to the market and our Core Values.

We’re a remote first company, with teammates spread across the US. We support in-person gatherings, including co-working spaces and multi-day onsites, to build connections and move forward strategic initiatives. Expect to travel 2-4 times a year. For our team members in the Bay Area, who prefer to work in person we can offer a hybrid set up to work from the SF office on a flexible schedule.

Target Base Salary Range : $125K - $150K

The base salary PicnicHealth offers may vary depending upon the scope, complexity, and autonomy of the position and on the candidate’s job-related knowledge, skills, and experience. The total package will include equity, in addition to a full range of medical and / or other benefits, depending on the position offered. Pay and benefits are subject to change at any time, consistent with the terms of any applicable compensation or benefit plans.

You also get :

Equal Opportunity Statement

PicnicHealth is committed to promoting an inclusive work environment free of discrimination and harassment. We value a diverse and balanced team where everyone can belong.

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Do you have 5+ years of experience leading complex RFP responses within a CRO, real-world evidence vendor, or digital health company supporting life sciences clients?

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