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Lead Principal Investigator
Lead Principal InvestigatorPlexus Partners • San Francisco, CA, US
Lead Principal Investigator

Lead Principal Investigator

Plexus Partners • San Francisco, CA, US
[job_card.variable_hours_ago]
[job_preview.job_type]
  • [job_card.full_time]
[job_card.job_description]

Job Description

We are searching for a Lead Principal Investigator to oversee a fast-growing clinical research site in San Francisco. This is a critical leadership role with direct impact on sponsor confidence, patient recruitment, and continuity of studies across a diverse therapeutic portfolio.

In this role, you will :

  • Provide medical leadership across a broad range of studies.
  • Serve as Principal Investigator on multiple trials.
  • Oversee and mentor a team of Principal and Sub-Investigators.
  • Build trust with patients, sponsors, and regulatory bodies through credibility and leadership.
  • Help drive the growth and expansion of a high-demand clinical research site.

The Ideal Profile

  • MD / DO (additional therapeutic range strongly preferred).
  • 5+ years of direct patient care experience.
  • 2+ years of hands-on clinical research experience as a PI.
  • Demonstrated ability to attract patients or sponsors through strong reputation and track record.
  • Collaborative leadership style with the ability to guide investigators and clinical staff.

    • Compensation & Benefits

  • Competitive salary based on experience.
  • 20% annual bonus linked to site revenue and performance goals.
  • Relocation sign-on bonus available for non-local candidates.
  • Strategic influence within a high-growth, well-respected research environment.

    • Why This Role?

    This opportunity is ideal for a senior physician who wants to :

  • Oversee a diverse therapeutic portfolio.
  • Join a fast-growing site with strong sponsor demand and significant year-over-year revenue growth.
  • Shape the future of a clinical research team positioned for long-term success.

    • Next Steps

    If you meet the requirements and are open to exploring this opportunity, please apply confidentially for a discreet discussion.

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