Senior Director, Commercial Technology AI Product Management

Job Description

Vertex is seeking a strategic Senior Director to lead AI Product Management within our Commercial Technology organization. This role will be responsible for building and managing a portfolio of high‑value commercial AI products that automate operations, accelerate patient access, and enhance customer experience. The Senior Director will define and drive the AI strategy, lead the development and adoption of agentic AI‑powered solutions, and collaborate closely with business engagement and platform teams to deliver measurable value. A key focus will be on defining and tracking the impact of AI investments, fostering upskilling and capability building across the functional teams to ensure successful adoption of AI and GenAI capabilities.

Key Duties and Responsibilities

• Define and lead the AI product vision, roadmap, and lifecycle for commercial technology initiatives.
• Translate complex business needs into scalable AI solutions that drive measurable value across marketing, market access, and field operations.
• Partner with Commercial, Data Science, IT, and external stakeholders to identify high‑impact AI opportunities aligned with business goals.
• Lead cross‑functional teams through the full product lifecycle—from ideation and design to development, deployment, and optimization.
• Horizon scan and identify emerging AI technologies, build and manage AI product roadmap, and drive adoption of cutting‑edge autonomous commercial solutions.
• Ensure AI products meet compliance, legal, and ethical standards, including data privacy and regulatory requirements.
• Champion a culture of innovation, experimentation, and continuous improvement in AI product development.
• Serve as a trusted advisor to senior leadership, providing insights and recommendations grounded in data and commercial strategy.

Knowledge and Skills

Education and Experience

Pay Range

$236,000 - $354,000

Disclosure Statement

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job‑related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market‑leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week‑long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation

Hybrid-Eligible Or On‑Site Eligible

Flex Eligibility Status

In this Hybrid-Eligible role, you can choose to be designated as :

Note : The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E‑Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and / or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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