ABOUT THE COMPANY
Marea Therapeutics is a clinical-stage biotechnology company based in South San Francisco with a growing pipeline of first-in-class therapies to address genetically validated cardioendocrine disease targets. Our therapies have the potential to complement existing therapies and serve as transformative treatment options for significant patient populations living with cardioendocrine diseases.
Incubated by Third Rock Ventures, Marea completed a Series B financing in June 2024 and is well funded by a syndicate of leading life science investors including Sofinnova, Forbion, Xontogeny / Perceptive Advisors, venBio, Omega Funds, Surveyor, Alpha Wave and Third Rock Ventures.
The company’s lead program, MAR001, is a monoclonal antibody targeting ANGPTL4, a genetically validated target with potential to address the subset of patients at the highest risk of adverse cardiovascular events, despite current standard of care therapies. MAR001 is rapidly progressing through Phase 2b clinical development. Our second clinical asset, MAR002, is a monoclonal antibody targeting excess growth hormone produced by the pituitary gland in the rare hormonal disorder, acromegaly. MAR002 has potential to become best-in-disease and is rapidly progressing through Phase 1 clinical development. We also have a third asset that is rapidly advancing through research discovery, with DC nomination expected next year.
At Marea, we believe in the power of collaboration and the importance of leading by example. We are a tight-knit team that values the contributions of every member, from interns to senior leaders. Our environment is dynamic, with each day presenting new challenges and opportunities for growth. Every role is “Hands-On”, and the successful candidate will be able to work alongside team members, regardless of level, to understand challenges and drive results.
About the Role
The Associate Director / Director, Program Management will have both early and late phase pharmaceutical program management experience that includes knowledge of drug development processes and interdependencies of key functions including research, translational medicine, clinical, regulatory, and CMC.
The successful candidate should have strong project management skills, have the highest levels of scientific and ethical integrity, be self-motivated, and enjoy working in a dynamic, fast-paced biotechnology environment to support the development of transformational therapies for cardiometabolic diseases.
This is an full-time, San Francisco based position with the expectation of working onsite at least three days per week. The level of the role will be commensurate with the chosen applicant’s background and experience.
Key Responsibilities
Cross-Functional Program Team and Sub-teams
- Partner with program team leader and other team members to develop the program vision, strategy, and goals / objectives
- Lead and develop the cross-functional program plan including key assumptions, realistic but aggressive timeline, budget and resource planning, risk and mitigation assessment, and contingency planning
- Support and / or run effective program team (and sub-team) meetings, driving toward cross functional alignment and support for the execution of the program plan
- Partner closely with the program team leader (and research team leader for early development assets) to proactively identify and remove bottlenecks, surface and resolve issues, and help teams through technical and program challenges as they arise
- Coordinate and reconcile project team inputs to key project documents, e.g., presentations to leadership or the board of directors
- Promote curiosity, scientific rigor, and excellent problem-solving skills across a fast-paced, performance-driven environment
Program Tracking
Develop, maintain and update the project plan through the course of the project, ensuring plan is phase appropriate, interdependency-linked, and aligned to program goals / strategic imperativesManage and maintain complete and high-quality core program information and documents such as minutes, agendas, action items, development plans, integrated timelines, assumptions, dashboardsProactively track and transparently report on program status against approved timeline, goals, and milestonesServe as a central source for cross functional program information across the company including to senior managementAssist VP of Program and Portfolio Management with departmental processes, procedures and tools to improve departmental functioning and program managementQualifications
Degree(s) in science, engineering, and / or business (e.g., BS, MS, PhD, MD, MBA) or equivalent curriculum. Persons without formal degrees who have comparable depth and breadth of training and experience and meet job-specific criteria may be eligible for consideration5+ years of drug development project management experience with the following experiences a plus :Experience in both mid-large and small start-up companiesPMP certificationPrior experience in a line function (e.g. research, clin ops, CMC, BD, regulatory)Project management of both early (ED - Ph 1) and late stage (Ph 2-3) programsRare disease drug developmentBasic understanding of each of the functional areas on a drug development project team, and of the key deliverables as a project progresses in developmentAbility to work independently and apply knowledge of project management principles to develop and progress plans, engage and influence team members and functional leaders, and develop proposals to solve day-to-say problemsFamiliarity with pre-clinical and clinical regulatory requirements and compliance standardsExpertise with project planning tools (e.g. Smartsheet, Planisware, etc.)Excellent interpersonal, communication, presentation skills, and executive presenceAbility to assess the accuracy, clarity, and thoroughness of the work assignedStrong problem-solving skills, with the ability to anticipate challenges and implement effective solutionsFlexibility and adaptability to work under pressure in a fast-paced early biotech environment with tight deadlinesMust be science- and data-driven and have the highest personal values and ethical standardsHighly motivated, proactive, enthusiastic and goal orientated to deliver on the success of pipeline molecules and companyPAY RANGE
The salary range for this role is $160,000 - $240,000. Compensation and title will be competitive and commensurate with the candidate's experience, qualifications, and the responsibilities of the position.
WORKING CONDITIONS
Prolonged periods of being at a stationary desk or work computerAbility to occasionally adjust, handle, or move objects up to [20] poundsTransparently and timely communicating with others to exchange informationOccasional travel as required to meet business objectives#LI-Hybrid
We do not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity or expression, national origin, age, disability, veteran status, marital status, or based on an individual’s status in any group or class protected by applicable federal, state, and local law. We invite applications from minorities, women, the disabled, protected veterans, and all other qualified applicants.