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Senior Scientist / Associate Principal Scientist, Chemical Engineering R&D
Senior Scientist / Associate Principal Scientist, Chemical Engineering R&DPharmaron • Coventry, RI, USA
Senior Scientist / Associate Principal Scientist, Chemical Engineering R&D

Senior Scientist / Associate Principal Scientist, Chemical Engineering R&D

Pharmaron • Coventry, RI, USA
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Job Title : Senior Scientist / Associate Principal Scientist, Chemical Engineering R&D

Location : Pharmaron, Coventry, RI

FLSA Status : Exempt

Salary : $100,000-$160,0000

Pharmaron is a global CRO helping pharma and biotech companies bring new therapies to life. With over 21,000 employees worldwide across 23 locations in the US, UK and China, we support drug discovery through to manufacturing with fully integrated, high-quality services.

We're proud of the impact we make and just last year, we supported over 780 discovery projects, 1,000+ CMC programmes, and 1,000+ clinical trials across all phases. Our teams are involved in everything from small molecules to biologics and gene therapies, and we work with more than 3,000 global customers. To learn more, visit .

About the Role

The Pharmaron Process Chemistry department is seeking highly motivated Chemical Engineers for an exciting role involving hands-on small-molecule process development and scale-up from laboratory to commercial manufacturing. Engineers in this position will design, plan, and implement both chemistry laboratory and in-silico experiments to support process and technology development for active pharmaceutical ingredients (APIs). This position will combine elements of chemistry, engineering, technology development, and data analysis to optimize manufacturing processes.

Strong teamwork, innovation, creativity, and organizational skills are essential, along with clear and confident communication to address technical challenges. Effective collaboration across multidisciplinary teams in the US, UK, and China, is critical, and a strong commitment to safety, quality compliance, and technical leadership is expected throughout all activities.

Key Responsibilities

  • Perform hands-on small molecule process development and scale-up work.
  • Use Design of Experiments (DoE) for process screening, optimization, and robustness studies.
  • Define CPPs, PARs, NORs, and contribute to the development of scalable control strategies.
  • Apply process analytical technology (PAT) and process modeling.
  • Evaluate and model kinetics, mixing, mass / heat transfer, and reactor performance.
  • Conduct independent research to achieve mechanistic understanding for rational process design.
  • Design and optimize key unit operations including crystallization, filtration, drying, distillation, and extraction.
  • Use process modeling tools to inform scale-up strategies.
  • Translate lab-scale findings into actionable parameters for kilo lab and GMP manufacturing.
  • Drive cycle time reduction and process intensification initiatives.
  • Implement innovative technologies such as continuous flow chemistry and automation platforms.
  • Support internal and external tech transfer activities, including scale-up studies, modeling, and verification experiments.
  • Support development of complex transformations such as catalytic hydrogenation.
  • Exhibit a mindset of safety and quality compliance.
  • Collaborate cross-functionally within US, UK, and China-based teams.

Required Experience & Skills

Education Minimum Requirement : The position requires either a BS and / or MS in Chemical Engineering (or comparable) from an accredited college / university plus at least 5 years of relevant work experience in small-molecule chemical process development - OR - a PhD in Chemical Engineering (or comparable) from an accredited college / university with at least 2 years of relevant work experience post PhD defense.

  • Experience performing lab-based research / process development in a chemical engineering-related area.
  • Experience with organic chemical synthesis and wet chemistry.
  • Experience with small molecule pharmaceutical drug substance development.
  • Experience applying statistical experimental design (i.e. Design of Experiments) and / or process modeling.
  • A high level of innovation, creativity, and self-initiative.
  • Highly effective communication and collaboration skills.
  • Good organizational, interpersonal, writing, and time management skills.
  • Preferred Experience & Skills

  • Experience with process scale-up and / or technology transfer, moving from laboratory to pilot plant or production scale.
  • Familiarity with concepts and application of cGMP and GDP during pharmaceutical development and production.
  • Demonstrated experience with chemical engineering-related technology development.
  • Familiarity with kilo-scale laboratory equipment.
  • Experience with process modeling (e.g., population balance modeling, distillation modeling).
  • Knowledge with milling equipment (spiral jet mills, pin mills, co-mills, rotor-stator wet mills).
  • Why Pharmaron?

    Collaborative Culture : Thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators.

    Benefits : As part of our commitment to your well-being, we offer a comprehensive benefits package :

  • Insurance including Medical, Dental & Vision with significant employer contributions
  • Employer-funded Health Reimbursement Account
  • Healthcare & Dependent Care Flexible Spending Accounts
  • 100% Employer-paid Employee Life and AD&D Insurance, Short and Long Term Disability Insurance
  • 401k plan with generous employer match
  • Access to an Employee Assistance Program
  • How to Apply :

    Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today!

    Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 21,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China.

    As an Equal Employment Opportunity and Affirmative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences.

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