Clinical Pharmacology Lead, Manager

Clinical Pharmacology Lead (Manager)

OVERVIEW :

Exciting opportunity in Clinical Pharmacology! Our Clinical Pharmacology Team is looking for a Manager to support the exciting portfolio in Internal Medicine. Our team members champion the innovative use of MIDD for efficient drug development and robust decision-making. A great environment for learning and professional growth!

ROLE SUMMARY :

Our Clinical Pharmacology Leads have key roles to play in influencing the discovery and development of drugs. Pfizer is a leader in model informed drug discovery and development (MIDD) and we are expanding in influence and impact. We have an open position as Clinical Pharmacology Lead supporting our End-to-End Internal Medicine portfolio. The ideal candidate is responsible for providing the clinical pharmacology and MIDD components of clinical plans and provide clinical pharmacology expertise to the project team and regulatory interactions. Working with multifunctional study team Clinical Pharmacology Leads utilize innovative methods to integrate knowledge of pharmacokinetics pharmacodynamics patient characteristics and diseases for rational development strategies and decisions as well as optimal study designs and dosage regimen selections.

ROLE RESPONSIBILITIES :

Act as Clinical Pharmacology representative on Clinical Sub Team Development Team and other multifunctional teams as appropriate.

Responsible for providing expertise leadership and deliverables of clinical pharmacology for the assigned projects within sphere of influence.

With some guidance design and execute clinical pharmacology plans and implement clinical pharmacology best practices on project teams.

Work closely with other disciplines to ensure that sufficient preclinical PK / PD knowledge exists to underwrite safe human administration and to establish the structure of a predictive model prior to FIH.

With some guidance responsible for planning and overseeing clinical pharmacology aspects at the project level (e.g clinical development plan implementation and interpretation of PK / PD analyses PK / immunogenicity / biomarker measurement strategies etc.).

Plan and oversee study level activities including protocol authoring clinical phase oversight and reporting.

With some guidance responsible (with clinicians and statisticians) for ensuring appropriate dose-range finding strategies which ultimately will lead to optimal doses and dosage regimens in patients.

Accountable for ensuring appropriate design and implementation of End-to-End MIDD plan that conforms with best practices.

Responsible for ensuring use of innovative analytical methods to integrate knowledge of PK PD patient characteristics and disease states to optimize doses dosage regimens and study designs.

With some guidance provide End-to-End clinical pharmacology contribution to regulatory documents (e.g. Briefing documents Regulatory queries Investigators Brochures IND NDA / MAA etc.).

Stay abreast of literature regulatory guidelines and internal guidances and SOPs.

Influence external environment through publications presentations and representation at scientific societies and industrial consortium.

BASIC QUALIFICATIONS :

Pharm. D. M.D. / Ph.D. or equivalent training / experience in pharmacokinetics pharmacometrics clinical pharmacology engineering or related discipline.

Strong quantitative skills and expertise (e.g. experience in mechanistic PK / PD modeling / systemspharmacology literature meta-analyses population modeling and clinical trial simulations using NONMEM R etc.).

0 years of industry experience

Excellent written and verbal communication skills.

Demonstrated presentation skills

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including the ability to influence and collaborate with peers to achieve meaningful outcomes and create business impact.

Additional Job Details :

Last date to apply is : December 17 2025

Work Location Assignment : This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week or more as needed.

The annual base salary for this position ranges from $102900.00 to $171500.00. In addition this position is eligible for participation in Pfizers Global Performance Plan with a bonus target of 15.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of lifes moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution paid vacation holiday and personal days paid caregiver / parental and medical leave and health benefits to include medical prescription drug dental and vision coverage. Learn more at Pfizer Candidate Site U.S. Benefits (). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa FL or any location outside of the United States.

Relocation assistance may be available based on business needs and / or eligibility.

Sunshine Act

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race color religion sex sexual orientation age gender identity or gender expression national origin disability or veteran status. Pfizer also complies with all applicable national state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

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Medical

Required Experience :

Manager

Key Skills

Administrative Skills,Facilities Management,Biotechnology,Creative Production,Design And Estimation,Architecture

Employment Type : Full-Time

Experience : years

Vacancy : 1

Monthly Salary Salary : 102900 - 171500