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- (Boston)Hengrui Pharma • Boston, MA, United States
- (Boston)

- (Boston)

Hengrui Pharma • Boston, MA, United States
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Process Development & Optimization

  • / / / / Lead downstream purification process development and optimization for biologics, including depth filtration, chromatography (affinity / ion exchange / hydrophobic interaction), ultrafiltration / diafiltration, virus inactivation / removal, etc.
  • CQACPPAnalyze Critical Quality Attributes (CQA) and Critical Process Parameters (CPP) during purification, addressing challenges in yield, purity, host cell protein (HCP) residues, etc.

Technology Transfer & Regulatory Submissions

  • AKTAGMPParticipate in pilot-scale purification process development (e.g., operation of AKTA systems), complete process scale-up and technology transfer to GMP manufacturing.
  • SOPIND / BLADevelop technical documentation (process protocols, SOPs, validation protocols) and support IND / BLA submission dossier preparation.

    • Platform Development & Management

  • Evaluate novel purification technologies (e.g., continuous flow chromatography, membrane chromatography) for potential implementation.
  • Oversee daily instrument maintenance and other downstream process development-related tasks.
  • Masters degree or above in Bioengineering, Biochemistry, Pharmaceutical Engineering, or related disciplines.
  • Research projects involving protein purification experiments, with hands-on experience in operating relevant instruments.
  • Strong English proficiency (listening, speaking, reading, writing), capable of fluently interpreting English technical literature and conducting technical communication with international peers.

    • / / / Shanghai / Suzhou / Guangzhou / Lianyungang

  • 1Western BlotAKTAProficient in fundamental experimental techniques (e.g., column packing , Western Blot ); Priority given to candidates with AKTA system operation experience .
  • 2Understanding of downstream purification workflows (e.g., affinity chromatography, ion exchange).
  • 3Excel / UNICORNBasic data analysis capabilities (Excel / UNICORN software).
  • Strong learning agility and deep interest in biopharmaceutical process development.
  • Systematic thinking and data analysis skills, adaptable to fast-paced R&D environments.
  • Independent problem-solving skills and cross-departmental collaboration mindset.
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