Senior Director, Business Insights and Analytics

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.

Reporting to the Chief Commercial Officer, the Senior Director, Business Insights and Analytics will play a pivotal role in shaping the company's data-driven decision-making capabilities. You will lead the development of an analytics function that will provide critical insights to support the launch of our first medicine, ESK-001 and the long-term commercial strategy. This position will involve building and leading the analytics infrastructure, leveraging data to optimize business processes, guide strategic decisions, and measure the effectiveness of our commercial and clinical initiatives. You will collaborate closely with senior leadership and cross-functional teams, including Commercial, Marketing, Sales, Medical Affairs, and R&D, to ensure the successful launch and ongoing success of our medicine.

The preference for this role is to be located in our South San Francisco headquarters.

Key Responsibilities

Analytics Strategy & Capability Building

Define and implement a scalable analytics strategy to support launch readiness, lifecycle management, and commercial excellence. Build and lead high-performing teams across forecasting, insights, market research, and advanced analytics. Drive the adoption of analytics across the organization and elevate data-driven decision-making culture.

Launch Insights & Market Research

Lead the generation of actionable insights to inform launch strategy, including customer segmentation, market landscape assessments, and stakeholder research (HCP, patient, payer). Translate insights into strategic recommendations to guide clinical, marketing, and access decisions.

Forecasting & Commercial Planning

Oversee forecasting for pipeline and in-line assets across multiple indications and geographies. Develop scenario models and sensitivity analyses to inform strategic planning and resource allocation.

Advanced Analytics & AI

Leverage AI/ML and advanced analytics (e.g., predictive modeling, patient journey analytics) to generate forward-looking insights and optimize commercial performance.

Data Infrastructure & Business Intelligence

Lead the design and implementation of scalable data infrastructure and governance to support real-time reporting, analytics, and insight generation. Integrate multiple data sources (market research, secondary, claims, RWE) to deliver executive-level dashboards and strategic insights.

Cross-Functional Collaboration

Partner with Commercial, Market Access, Medical Affairs, R&D, Finance, and Supply Chain teams to align analytics with business strategy and operational priorities. Lead enterprise-level data initiatives, including Master Data Management and cross-functional analytics platforms.

Portfolio & Lifecycle Strategy

Inform portfolio decisions across the development continuum—TPP refinement, indication prioritization, launch planning, and post-launch optimization.

Executive Leadership & Influence

Serve as a strategic advisor to the CCO and executive leadership team on key commercial and investment decisions. Represent the analytics function in senior forums, shaping strategy through data-driven recommendations.

Must Have Skills/Experience

Requires a BA or BS (MS or MBA preferred) with 10+ years of data analysis, decision support, market research, and forecasting experience within the pharmaceutical, biotech, or healthcare sector. Demonstrated ability to think strategically while also able to act decisively and tactically. Strong project management skills and ability to work to deadlines successfully managing multiple business-driven data related initiatives. Understanding of the insight and data landscaping as it pertains to Marketing, Market Access and Medical Affairs and across the brand lifecycle. Demonstrated success working with Digital / Technology teams to build future capabilities that are fit for purpose, effective and differentiating. Practical experience with implementing and optimizing AI technologies in biotech or pharmaceutical industry.

The salary range for this position is $245,000 - $300,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.

This position is located in South San Francisco, CA and employees are expected to be onsite Tuesday-Thursday. Open to remote applicants with requirement to be onsite once a month.

Alumis Inc. is an equal opportunity employer.

Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.

Other benefits include:

Health insurance premiums paid at 90% for employee, 80% for dependents Free access to Genentech Bus & Ferry Share program $100 monthly cell phone stipend Unlimited PTO for Exempt employees Free onsite gym and a kitchen stocked with yummy snacks and drinks!

We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way.