Director, Health Economics and Outcomes Research

Real-World Evidence Director

Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully-integrated endocrine company from discovery to patients. Join our team as we transform the lives of others.

Position Summary

The Real-World Evidence Director will be responsible for evidence generation to support the Paltusotine program throughout its lifecycle management. The Director will design, implement, and manage HEOR studies, including observational studies, claims analyses, chart reviews, survey research and other complementary analyses to support value proposition for Paltusotine. The RWE Director will closely collaborate with cross-functional partners including Regulatory, Clinical Research, Clinical Operations, Biometrics, Medical Affairs, Patient Advocacy, and Commercial to successfully incorporate HEOR strategies and evidence generation to support the development and commercialization of our asset in acromegaly. In addition, this role will collaborate externally with academic and / or clinical partners.

Essential Job Functions and Responsibilities

These may include but are not limited to :

• Focus on immediate and short-term (
• Provide leadership, career management, coaching and mentoring to others on the team and cross-functionally
• Drive team objectives and goal setting, prioritization, and adherence to plan and strategy
• Develop HEOR research strategies that support the value proposition for product launches, label expansions, and US & EU market access
• Build value materials to meet evidentiary requirements (i.e. RWE case control studies, literature reviews etc.)
• Perform analysis using real-world large healthcare databases (e.g., insurance claims, electronic health records, retrospective and prospective database analyses)
• Conduct literature search, review and synthesis; review and critique medical and evidence-based outcomes literature & analyses
• Collaborate with internal interdisciplinary teams and external partners to understand and meet needs of key partner evidentiary requirements
• Communicate regularly with internal and external stakeholders to ensure all parties are up to date on the HEOR & RWE information relevant to them, including strategies, and progress
• Strengthen partnerships with stakeholders within the organization and externally with data providers, platform vendors, healthcare providers, payers, FDA etc.
• Collaborate with researchers and expert contributors to assess and recommend data opportunities; lead data strategy working group operations supporting data assessments with functional subject matter experts (SMEs).
• Other duties as assigned.

Education and Experience

Required :

Physical Demands and Work Environment

Physical Activities : On a continuous basis, sit at desk for a long period of time; intermittently answer telephone and write or use a keyboard to communicate through written means. Some walking and lifting up to 25 lbs. may be required. The noise level in the work environment is typically low to moderate. The physical demands described above are representative of those that must be met by an employee to successfully perform the essential functions and responsibilities.

Laboratory Activities (if applicable) : Biology and chemical laboratory environment experience needed. Environmental health and safety requirements also apply.

Travel : You may be required to travel for up to 5% of your time.

The Anticipated Base Salary Range

In addition to your base pay, our total rewards program consists of a discretionary annual target bonus, stock options, ESPP, and 401k match. We also provide top-notch health insurance plans for employees (and their families) to include medical, dental, vision and basic life insurance, 20 days of PTO, 10 paid holidays, and a winter company shutdown.

The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience and education. Crinetics Pharmaceuticals is a multi-state employer, and this salary range may not reflect positions that work in other states. Your recruiter can share more about the specific salary range during the hiring process.

Equal Opportunity Employer

Crinetics is proud to be an Equal Opportunity Employer. We provide equal employment opportunities to all employees and employment applicants without regard to unlawful considerations of sex, sexual orientation, gender (including gender identity and / or expression), pregnancy, race, color, creed, national or ethnic origin, citizenship status, religion or similar philosophical beliefs, disability, marital and civil union status, age, genetic information, veteran status or any personal attribute or characteristic that is protected by applicable local, state or federal laws.

The salary range for this position is : $199,000 - $249,000. In addition to your base pay, our total rewards program consists of a discretionary annual target bonus, stock options, ESPP, and 401k match. We also provide top-notch health insurance plans for employees (and their families) to include medical, dental, vision and basic life insurance, 20 days of PTO, 10 paid holidays, and a winter company shutdown.