Bioinformatics Analyst - Quality Control / Variant Interpretation (Weekend AM shifts required)

Passionate about precision medicine and advancing the healthcare industry?

We are seeking a highly motivated and capable bioinformatics analyst with experience and interest in translational cancer research and next-gen sequencing clinical diagnostics. This position requires experience with cancer genomics, bioinformatic pipelines, genomic variant interpretation, and relational data systems. Top candidates will also have experience deploying bioinformatics code and retrieving relevant data from relational databases.

Duties and Responsibilities :

• Provide bioinformatics support for quality control and variant identification / interpretation, prior to clinical case sign-outs.
• Evaluate sample and variant metrics to confirm data quality and integrity.
• Provide timely notifications to laboratory and clinical personnel regarding potential sample irregularities.
• Interpretation of single-nucleotide, insertion / deletion, and copy number variants, as well as variants predictive of protein fusion events, in both DNA and RNA data
• Responsible for identifying and interpreting complex variant calls in low coverage, variable, and novel genomic regions, in addition to sequencing artifacts.
• Use SQL and other scripting languages to retrieve relevant data from various bioinformatics databases.
• Use Python to perform analyses on genomic data sets and maintain internal tools
• Communicate findings in a clear and logical manner to help stakeholders make scientific and clinical decisions based on your interpretation of variant data
• Produce high-quality, detailed documentation for analyses / projects
• Track variant data through multiple systems, utilize code searches, and review documentation, to understand how a result was produced.

Required Experience :

Ideal candidates will possess :

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We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Additionally, for remote roles open to individuals in unincorporated Los Angeles – including remote roles- Tempus reasonably believes that criminal history may have a direct, adverse and negative relationship on the following job duties, potentially resulting in the withdrawal of the conditional offer of employment : engaging positively with customers and other employees; accessing confidential information, including intellectual property, trade secrets, and protected health information; and appropriately handling such information in accordance with legal and ethical standards. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.