Senior Director, Global Commercial Strategy - CF Pipeline Lead

Job Description

Vertex operates at the forefront of scientific innovation. It has seven approved medicines : five that treat the underlying cause of cystic fibrosis ("CF"), a life‑threatening genetic disease, one that treats severe sickle cell disease ("SCD") and transfusion dependent beta thalassemia ("TDT"), and one that treats moderate-to-severe acute pain. Our clinical‑stage pipeline includes programs in CF, SCD, beta thalassemia, acute and peripheral neuropathic pain, APOL1-mediated kidney disease, IgA nephropathy and other autoimmune renal diseases and cytopenias, type 1 diabetes, muscular dystrophy, and autosomal dominant polycystic kidney disease.

General Summary

The Senior Director, Global Commercial Strategy CF Pipeline Lead is accountable for understanding the evolving needs of the CF Community and Vertex’s position within a potentially competitive market, actively contributing to defining the pipeline strategy, pipeline performance goals, and tracking performance against those goals.

Key Duties and Responsibilities

• Develop the pipeline strategy (e.g., Next Generation 3.0 and mRNA therapies) and oversee creation of brand strategies and lifecycle activities including data generation to support differentiation and commercialization goals.
• Oversee development and implementation of strategic and tactical plans for next generation CFTR modulators and mRNA therapies.
• Identify the commercial opportunity for further serial innovation.
• Lead team through challenges related to creating external promotional communication materials for external use with customers.
• Provide input into forecasting assumptions and evaluate ROI for activities across the pipeline.
• Generate and consolidate key insights across HCPs and patient stakeholders through market research, ad boards, etc.
• Lead the development of brand name for Next Generation 3.0 and VX 522.
• Lead the development of strong collaborative partnerships with cross‑functional team(s) to support business goals.
• May lead complex projects that are cross‑functional in nature.

Knowledge and Skills

Education and Experience

Pay Range

$225,600 – $338,400

Disclosure Statement

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job‑related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market‑leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week‑long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation

Hybrid-Eligible or On‑Site Eligible

Flex Eligibility Status

In this Hybrid-Eligible role, you can choose to be designated as :

Note : The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

EEO Statement

Vertex is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E‑Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and / or to perform the essential functions of the position should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

#J-18808-Ljbffr