DIRECTOR OF CLINICAL RESEARCH

Director of Clinical Research

Location: Philadelphia, PA (On-site)
Organization: Mazzoni Center

About Mazzoni Center

Mazzoni Center is Philadelphia’s premier health and wellness center focused on providing compassionate, comprehensive care for the LGBTQ+ community. Our mission extends beyond healthcare — we are dedicated to advancing equity, inclusion, and community-driven innovation in every aspect of our work.

Position Summary

Mazzoni Center is seeking a Director of Clinical Research to lead and oversee our growing portfolio of clinical studies. This individual will manage all aspects of clinical research operations — from sponsor coordination and regulatory compliance to staff leadership and community engagement.

The ideal candidate is a dynamic, mission-driven leader with deep expertise in clinical research and a strong commitment to inclusive, community-engaged research that benefits the populations we serve.

Key Responsibilities

• Oversee all clinical research operations, including staffing, resources, timelines, and budgets.
• Ensure full compliance with FDA, ICH-GCP, and other regulatory and ethical standards.
• Develop and maintain quality systems aligned with core Risk-Based Quality Management principles.
• Lead, motivate, and mentor a multidisciplinary research team (investigators, nurses, coordinators).
• Partner with sponsors, CROs, and other collaborators to ensure successful study execution.
• Conduct and oversee participant assessments, recruitment, and retention efforts.
• Ensure data accuracy, integrity, and timely reporting across all studies.
• Identify risks and implement mitigation strategies to maintain study quality and safety.
• Foster transparent, equitable partnerships with community stakeholders, ensuring that research outcomes are both academically rigorous and socially impactful.
• Drive continuous process improvement in research operations and quality management.

Qualifications

Education & Training

• Registered Nursing or Public Health degree required; MSN or MPH preferred.
• At least 5 years of clinical research experience, including 3 years in a supervisory or leadership role.
• Certified Clinical Research Professional (CCRP) or equivalent certification required.

Experience & Skills

• Nurse Practioner/PA Preferred
• Proven leadership in clinical research operations and compliance with international and U.S. regulatory standards.
• Expertise in developing and implementing clinical research policies, SOPs, and systems.
• Strong interpersonal, coaching, and communication skills with the ability to foster collaboration and resolve conflict.
• Demonstrated success in building inclusive, high-performing teams.
• Commitment to the values of community engagement, transparency, and equity in research.

Clearances

All candidates must successfully complete:

• Criminal Background Check
• Child Abuse Clearance
• FBI Clearance

Physical Requirements

• Ability to sit, stand, and walk for extended periods.
• Ability to lift up to 20 lbs.
• Ability to communicate effectively in both written and spoken English.

Why Join Mazzoni Center?

• Be part of a mission-driven organization advancing health equity and LGBTQ+ representation in research.
• Lead a dedicated and passionate team in a collaborative, inclusive environment.
• Shape the future of community-engaged clinical research in Philadelphia and beyond.

Join us in making a difference.
Apply today to lead meaningful research that drives impact — for science, for equity, and for community