Clinical Trial Manager

Job Description

Job Description

Description :

Marea Therapeutics is a clinical-stage biotechnology company based in San Francisco with a growing pipeline of first-in-class therapies to address genetically validated cardiometabolic disease targets. Our therapies have the potential to complement existing therapies and serve as transformative treatment options for significant patient populations living with cardiometabolic diseases.

Incubated by Third Rock Ventures, Marea completed a Series B financing in June 2024 and is well funded by a syndicate of life science investors including Sofinnova, Forbion, Perceptive Advisors, Xontogeny, venBio, Omega Funds, Surveyor, Alpha Wave and Third Rock Ventures. The company’s lead program is in Phase 2 clinical development (MAR001) and a second program is progressing towards clinical development in a rare cardiometabolic disease. Marea is a fast-growing company looking for extraordinary individuals to join our team who want to make a difference in the lives of millions of people living with cardiometabolic diseases. The company is led by a dynamic team of scientists and company builders with deep knowledge and experience in cardio-endocrine diseases, human genetics, and adipocyte biology.

At Marea, we believe in the power of collaboration and the importance of leading by example. We are a tight-knit team that values the contributions of every member, from interns to senior leaders. Our environment is dynamic, with each day presenting new challenges and opportunities for growth. Every role is “Hands-On”, and the successful candidate will be able to work alongside team members, regardless of level, to understand challenges and drive results.

SUMMARY

The Clinical Trial Manager will provide operational and technical expertise to help plan and execute Marea sponsored clinical trials in alignment with corporate goals and objectives. This individual will initially be asked to manage key operational management components of a global phase 2 trial for Marea’s leading cardiometabolic program under the supervision of the Marea Study Lead and may be asked to provide back-up support for other trials as needed. This individual will eventually take on a Study Lead role for new trials downstream. The Clinical Trial Manager will partner with the Clinical Operations Team to build and develop fit-for-purpose internal infrastructure and processes to support Marea-sponsored trials.

This is a full-time position, with a strong preference for candidates that can work on-site at least three days per week in the San Francisco-based office.

Requirements : Study Management

• Support global phase 2 Study Lead to ensure that all key trial milestones and activities are completed on-time and within budget, by managing key components of the trial.
• Support the development and maintenance of key trial documents such as protocols, ICFs, study plans, etc.
• Lead critical site and trial management activities such as ICF review, site activations, tracking monitoring visit scheduling, review monitoring visit reports.
• Generate and maintain internal trial management trackers and reports.

CRO & Vendor Oversight

Clinical Trial Quality & Compliance

Department Support

Mentor and support junior staff as needed.

QUALIFICATIONS