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Bioinformatics Engineer
Bioinformatics EngineerPharmaEssentia U.S.A. • Bedford, MA, US
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Bioinformatics Engineer

Bioinformatics Engineer

PharmaEssentia U.S.A. • Bedford, MA, US
[job_card.30_days_ago]
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  • [job_card.full_time]
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Job Description

Job Description
Job Description: Bioinformatics Engineer
Department: Data Science, PIRC
Reports to: Director of AI in Drug Development

Job Summary:
We are seeking a highly motivated and skilled Bioinformatics Engineer to join our dynamic data science team. In this role, you will be instrumental in supporting our drug discovery and development programs by building, deploying, and maintaining robust computational pipelines and frameworks. You will analyze complex, large-scale biological datasets (e.g., genomics, transcriptomics, proteomics) to help identify novel drug targets, discover predictive biomarkers, and understand disease mechanisms.
This position requires a strong technical background in data analysis, software engineering, and computational biology, combined with a passion for applying these skills to solve challenging problems in pharmaceutical research.

The Company:
It’s not often you get the chance to make a real impact on the lives of others, while expanding your own possibilities. You’ll find that rare opportunity at PharmaEssentia. Join us, and let’s transform lives, together.
PharmaEssentia Corporation is a rapidly growing biopharmaceutical innovator. We are leveraging deep expertise and proven scientific principles to deliver effective new biologics for challenging diseases in the areas of hematology and oncology, with one approved product and a diversifying pipeline. We believe in the potential to improve both health and quality of life for patients with limited options today through the combination of rigorous research and innovative thinking.
Founded in 2003 by a team of Taiwanese-American executives and renowned scientists from U.S. biotechnology and pharmaceutical companies, today we are listed on the Taipei Exchange (TPEx: 6446) and are expanding our global presence with operations in the U.S., Japan, China and Korea, along with a world-class biologics production facility in Taichung.
This role will be in the PharmaEssentia Innovation Research Center (PIRC), the US R&D center for PharmaEssentia. As PIRC is essentially in startup mode with the full backing of PharmaEssentia HQ, this is an exciting time for PIRC and the Data Scientist will have great influence in developing and growing PIRC from the ground floor up.

Key responsibilities
  • Pipeline & Framework Development: Design, build, optimize, and maintain scalable, reproducible bioinformatics pipelines for the processing and analysis of large-scale omics data. Build internal computational frameworks for multi-omics integration and visualization to generate novel biological insights.
  • Data Analysis: Perform comprehensive analysis of genomic and transcriptomic datasets and proteomics to support target identification, validation, and biomarker discovery efforts.
  • Tool & Infrastructure Management: Implement and manage computational tools, workflows, and databases. Utilize cloud computing and containerization technologies to ensure our infrastructure is efficient and scalable.
  • Collaboration: Work closely with cross-functional teams, including bench scientists, biologists, and clinicians, to understand experimental design, interpret complex data, and communicate effectively.
  • Innovation & Methodology: Stay current with the latest computational biology methods, algorithms, and software. Evaluate and implement new technologies to enhance our team's analytical capabilities.
  • Documentation: Maintain high-quality documentation for all code, pipelines, and analyses to ensure reproducibility and compliance.

Required Qualifications
  • Ph.D. in Bioinformatics, Computational Biology, Computer Science or relevant quantitative discipline
  • 2+ years of relevant post-graduate experience, preferably in a biotech or pharm setting
  • Strong programming skills with expertise in at least two of the following: Python, R, Java, C#.
  • Familiarity with database management (SQL, NoSQL)
  • Demonstrated experience in building and managing automated bioinformatics workflow
  • Working knowledge with machine learning algorithms, Deep learning frameworks, LLM and AI agent, and their applications in drug discovery
  • Familiarity with cloud computing platforms (AWS, GCP, or Azure) and HPC environments
  • Good understanding of biology
  • Excellent problem-solving abilities, strong communication skills and proven ability to collaborate effectively in a team-oriented, cross-functional environment

Preferred Qualifications
  • Experience in a therapeutic area relevant to oncology and immunology
  • Familiarity with software development best practices and version control
  • Experience with data lake


EEO Statement:
At PharmaEssentia Innovation Research Center (PIRC), we are committed to providing an environment of mutual respect where equal employment opportunities are available to all applicants without regard to race, color, religion, sex, pregnancy (including childbirth and related medical conditions), national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information (including characteristics and testing), military and veteran status, and any other characteristic protected by applicable law. PIRC believes that diversity and inclusion among our team are critical to our success as a global company, and we seek to recruit, develop and retain the most talented people from a diverse candidate pool. PIRC does not accept unsolicited agency resumes. Staffing agencies should not send resumes to our HR team or to any PIRC employees. PIRC is not responsible for any fees related to unsolicited resumes from staffing agencies.

At PharmaEssentia, our goal is to treat as many people with cancer as possible. That means challenging the status quo with better science that leads to better lives. By joining our team, you will not only expand your own possibilities, but you will contribute to expanding options for people with cancer.

https://us.pharmaessentia.com/careers/

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