Senior Scientist, Translational Research - Real World Data Science

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.Tempus' proprietary platform connects an entire ecosystem of real-world data to deliver real-time, actionable insights to physicians. Our data empowers researchers to better characterize and understand disease, and to drive better outcomes through precise, individualized care.

• Key Responsibilities :
• Execute Strategic Collaborations :
• Partner with our pharma clients to design, develop and execute computational research projects leveraging the Tempus platform to advance precision medicine research programs. + Execute scientific activities including scoping net new projects, generating high quality contracted deliverables and serve as the key scientific lead in the partnership. + Support exploratory research for target discovery and validation in early phases of drug development. + Support decisions for early stage assets such as patient and indication selection, biomarker and combination strategies. + Evaluate clinical trial design by testing assumptions, refining eligibility criteria, and characterize patient outcomes on standard of care. + Develop novel biomarkers of response signatures.
• Leadership Development :
• Help train and manage junior scientists on team
• Independent Contribution :
• Independently execute complex translational or real-world evidence research projects integrating molecular and clinical data from Tempus multimodal data platform to derive real-world insights for biopharma partners.
• Scientific Communication :
• Expert in navigating client interactions; Present scientific findings clearly and meaningfully to diverse sets of external stakeholders. + Document, summarize and communicate highly technical results and methods clearly to non-technical audiences. + Author abstracts, posters and peer-review publications to illustrate the value of multimodal analysis and AI in drug discovery in coordination with our partners or internal R&D teams.
• Continuous Improvement :
• Become an expert in our biopharma partners’ strategy, pipeline and portfolio to proactively determine all areas that the Tempus platform could add value to the drug development process of our partners. + Stay current with industry trends, best practices, and advancements in computational oncology research. Apply this knowledge to enhance research methodologies and improve overall research quality on the team. + Work with Product and Engineering teams to streamline workflow of computational analyses.
• Qualifications :
• Education : PhD degree in a quantitative discipline (e.g. Biostatistics / Statistical Genetics, Cancer Genetics, Bioinformatics, Computational Biology, Computational Immunology or similar) plus 2 years of experience or postdoctoral studies. Alternatively, a PhD in Molecular Biology or Immunology combined with a very strong record of computational biology.
• Experience : Minimum 2+ years in drug development leveraging genomic and multimodal data for drug discovery and development .
• Technical / Scientific Skills : Proficient in R, Python, and SQL. Strong understanding of cancer biology
• Communication Skills : Excellent written and verbal communication skills, with the ability to present complex information clearly and persuasively to diverse audiences.
• Preferred Skillsets / Background :
• Strong understanding of molecular data and artificial intelligence in drug discovery with experience in integrative modeling of multi-modal clinical and omics data.
• Previous experience working with large transcriptome and NGS data sets.
• Prior consulting and / or client facing experience is highly desirable
• Ability to work collaboratively in a team environment
• Thrive in a fast-paced environment and willing to shift priorities seamlessly.
• Experience with R package development.
• Strong peer-reviewed publication record.
• Experience with : Pandas, NumPy, SciPy, Scikit-learn, Jupyter Notebooks, RStudio, R Package development, tidyverse, ggplot, Git, matplotlib, seaborn, HTML5, CSS3, JavaScript, D3, Plot.ly, Flask, Dask, Docker, AWS.
• Goal orientation, self motivation, and drive to make a positive impact in healthcare.CHI : $130,000-$175,000 USD NYC / SF : $140,000-$190,000 USDThe expected salary range above is applicable if the role is performed from California and may vary for other locations (Colorado, Illinois, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.Additionally,
• for remote roles open to individuals in unincorporated Los Angeles
• – including remote roles-
• Tempus reasonably believes that criminal history may have a direct, adverse and negative relationship on the following job duties, potentially resulting in the withdrawal of the conditional offer of employment : engaging positively with customers and other employees; accessing confidential information, including intellectual property, trade secrets, and protected health information; and appropriately handling such information in accordance with legal and ethical standards. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.The Senior Scientist, Translational Research or Real-World Evidence in the Real World Data science org will design and execute research projects for early stage to mid stage biopharmaceutical partners. This role involves performing complex computational analyses, and providing interpreted insights in a consultative approach to guide decision-making for biopharma clients. This role will require staying up to date in research and industry trends in oncology drug development to identify specific areas where the Tempus platform can establish new markets.We’re looking for people who can change the world.Who question the status quo and don’t shy away from tough problems. For the builders who are never done building and the learners who are never done learning. We’re looking for passionate people with undying curiosity. Those who want to attack one of the most challenging problems mankind has ever faced. Head on.

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