Research Associate II – Neural Coding - Axonal Connectomics

The mission of the AllenInstitute is to understand the principles that govern life, and to advance health. Our creative and multi-dimensional teams focus on answering some of the biggest questions in bioscience. We accelerate foundational research, catalyze bold ideas, develop tools and models, and openly share our science to make a broad, transformational impact on the world.

The mission of the Allen Institute for Brain Science is to accelerate the understanding of how the human brain works in health and disease. Using a big science approach, we generate useful public resources, drive technological and analytical advances, and discover fundamental brain properties through the integration of experiments, modeling, and theory.

The goal of the Axonal Connectomics team, within the Neural Coding department, is to characterize the trajectories of projection axons, the wires connecting different brain areas, throughout the brain. The long-term aim is to provide such a map for the entire human brain, thus providing the first fine-grained map of brain-wide connectivity.

At the Allen Institute, we believe that science is for everyone – and should be open to everyone. We are dedicated to combating biases and reducing barriers to STEM careers more broadly.

We also believe that science is better when it includes different perspectives and voices. We strive to make the Allen Institute a place where everyone feels like they belong and are empowered to do their best work in a supportive environment.

We are an equal-opportunity employer and strongly encourage people from all backgrounds to apply for our open positions.

Essential Functions

• Perform basic tissue handling, including microtome-sectioning, mounting onto a slide, and coverslipping
• Use advanced histological procedures to antibody-stain, expand, and clear individual sections of the brain
• Coordinate with the imaging and computational teams to optimize sample preparation protocols and generate 3D data sets
• Receive and maintain records on tissue samples
• Image samples on light-sheet and confocal microscopes, perform production imaging as necessary
• Coordinate with collaborating teams, both within the Allen Institute and externally

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