Senior Research Associate (Assay Development and Manufacturing Associate) - Contract

Job Description

Job Description

About Us

DELFI Diagnostics, Inc. (DELFI Diagnostics) is developing next-generation, blood-based tests that are reliable, accessible and deliver a new way to help detect cancer. Employing advanced machine-learning methods to whole-genome sequencing data, the DELFI ("DNA EvaLuation of Fragments for early Interception") platform is built to address the highest-burden health challenges. DELFI Diagnostics prioritizes solutions that have the potential to save lives on a global scale, including for historically underserved populations. DELFI Diagnostics’ platform relies on fragmentomics – the discovery that cancer cells are more chaotic than normal cells and, when they die, leave behind tell-tale patterns and characteristics of cell-free DNA (cfDNA) fragments. FirstLook Lung, for individuals eligible for lung cancer screening, is DELFI Diagnostics’ first laboratory-developed screening test and can be part of routine blood work. FirstLook Lung uses millions of data points to reliably identify individuals who may have cancer detected through low-dose CT, including early stage disease with a negative predictive value of 99.8 percent. This test has not been cleared or approved by the FDA.

In our passionate pursuit to radically improve health outcomes, we serve humanity when we :

Lead with Science, Anchor in Pragmatism : We pioneer life-changing science by ensuring quality, transparency, and rigor at all times. We explore thoughtfully, experiment smartly, and deliver impact with conviction.

Build With & For All : We embrace diverse backgrounds to innovate and achieve together. We are not just building a product - we aim to disrupt the path of cancer for all - no matter geography or socioeconomic class

Put We over I : We are a home for high-performing people. Through teamwork, we build collective intelligence. Each of us wins when those we serve and those who serve with us win. We show up with empathy, humility, and integrity at every step of the journey.

About the Role

Join our innovative team dedicated to reducing cancer deaths through cutting-edge liquid biopsy diagnostics. As Sr. Research Associate, you will be responsible for performing functional quality control testing of incoming GMP-grade reagents, preparing manufacturing controls, and supporting our CLIA-certified laboratory operations. You will work with molecular and biochemical assays, utilizing automated liquid handling systems to ensure our manufacturing processes meet stringent quality standards. Additionally, you will support research and development activities as needed, contributing to method optimization and validation studies.

This contract position requires strong attention to detail and the ability to work in a regulated GMP / CLIA environment where precision and documentation are critical.

What you'll do

• Manufacturing & Quality Control
• Perform functional and other quality control testing on incoming reagents for molecular and biochemical assays with meticulous attention to detail and adherence to high-quality standards.
• Execute reagent qualification protocols following established SOPs and manufacturing procedures
• Prepare manufacturing controls and reference standards
• Operate automated liquid handling systems (Hamilton or similar platforms) for high-throughput reagent testing
• Maintain comprehensive documentation in compliance with FDA 21 CFR 820, GMP requirements, and CLIA regulations
• Track reagent lot numbers, expiration dates, and qualification results in inventory management systems

Research & Development Support :

Cross-Functional Collaboration :

What You'll Have Accomplished 6 Months From Now

What you'll bring to DELFI

Preferred qualifications :

An equal opportunity employerWe are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.