Senior Director, Analytical Development and Quality Control

Senior Director, Analytical Development And Quality Control

Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life.

Our single Altos value : Everyone Owns Achieving Our Inspiring Mission.

We believe that diverse perspectives are foundational to scientific innovation and inquiry. At Altos, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining a diverse and inclusive environment.

The Altos Institute of Medicine will capture knowledge generated about cell health and programming and develop transformative medicines. We are seeking a highly experienced analytical and QC leader to join the Technical Operations team as the Head of Analytical Development and Quality Control. The candidate will work in a highly dynamic and cross-functional environment that will have close collaboration with the Institutes of Science and span multiple therapeutic areas. The successful candidate will lead analytical development and quality control for Altos programs. Modalities include protein and antibody therapeutics, small molecules, antisense oligonucleotides, mRNA and AAV gene therapy.

Responsibilities

• Lead analytical development and quality control across multiple modalities
• Build a high performing team and establish internal and external analytical and QC capabilities
• Serve as CMC lead and analytical lead for Altos therapeutic programs
• Manage contract manufacturing organizations and CROs to develop and qualify analytical testing methods, perform product characterization, release and stability testing, and in-process testing
• Establish product specifications to ensure product quality. Support technical assessment of Out of Specification and Non-Conforming investigations.
• Author, review, and / or approve Standard Operating Procedures, specifications, regulatory filing, or other controlled documents
• As a member of the Tech Ops leadership team, build the Tech Ops organization, processes, systems and infrastructure
• Create and foster strong partnerships with Institutes of Science, Institutes of Technology, Institute of Computation, drug discovery and development sciences, clinical, regulatory, program management, business development, legal and finance
• Actively contribute to a team culture that promotes continuous improvement, accountability, professional growth, and inclusion

Qualifications

The salary range for Redwood City, CA :

Exact compensation may vary based on skills, experience, and location.

Altos Labs provides equal employment opportunities to all employees and applicants for employment, without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. Altos prohibits unlawful discrimination and harassment. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

Altos currently requires all employees to be fully vaccinated against COVID-19, subject to legally required exemptions (e.g., due to a medical condition or sincerely-held religious belief).