Research Associate, Protein Science

The Company
We are Alloy Therapeutics—a biotechnology ecosystem company empowering the global scientific community to make better medicines together. Through a community of partners, we democratize access to pre-competitive tools, technologies, services, and company creation capabilities that are foundational for discovering and developing therapeutic biologics. The company facilitates affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech, to the largest biopharma. At Alloy, we believe our industry should compete on getting the best drugs to patients as quickly as possible, not exclusive access to the best platforms. As a reflection of our relentless commitment to the scientific community, we reinvest 100% of our revenue in innovation and access to innovation. MAY THE BEST DRUG WIN.

Alloy is headquartered in Waltham, MA with additional labs in Cambridge, UK; Basel, Switzerland, and Athens, GA. Successful members thrive in our shared culture of accountability, deliberate trust, and open communication. As a team we aspire to work together to exceed expectations and collectively contribute across the global organization to always maintain our nimble, startup culture.

This is an on-site and full-time position in Athens, GA. At Alloy, we have an ethos of “Mentorship-By-Apprenticeship” in all of our positions. We strive to have workers in the office when needed to interact organically and face-to-face. Of course, as a lab-based operation, our cells and animals grow 7 days a week, 365 days per year. We respect and value our colleagues for their hard work that requires them to be in the lab every day. We ask our people who have more flexible accommodations, like this position, to appreciate their colleagues who have less flexibility. We are all one team!

The Role
As a Protein Science Research Associate, you will collaborate with seasoned drug discovery experts to help identify potential life-saving therapeutics. This role will report to the Senior Director of Protein Science, and it requires an experienced, hard-working, creative and organized scientist with a positive attitude. With protein science and biochemistry as your focus, you will work in a matrixed environment where your diverse skills will be applied to support all teams in the discovery workflow.

How You’ll Drive Impact

• Discover: Life-changing therapeutics through micro-scale, high-throughput antibody expression techniques.
• Innovate: Develop and refine cutting-edge protein expression workflows using high throughput methods.
• Organize: Experimental workflows, reagents, sample inventories, and data output with precision to ensure seamless lab operations.
• Collaborate: Closely with cross-functional teams to deliver high-quality data that drives key decision-making processes.
• Communicate: Experimental findings and provide actionable insights on novel protein expression to a matrixed team of researchers.

Principal Responsibilities

• Conduct protein expression workflows, including transfection of mammalian cells, purification of antibodies and other proteins and measurement of concentration of protein samples
• Maintain mammalian cells for high viability and cell health
• Prepare and execute protein purification techniques at large scale
• Maintain and operate protein expression and purification instruments to ensure consistent and accurate protein production.
• Design and execute experiments to troubleshoot and optimize workflows, ensuring reliability and efficiency in analytical processes.
• Collaborate with other departments, including protein analytics, molecular biology, and immunology, to align on project goals and timelines.
• Present experimental data and findings during team meetings, contributing to strategic decision-making processes.
• Maintain laboratory organization, ensure compliance with safety protocols, and manage reagent inventories.
• Stay current with emerging analytical techniques and technologies, incorporating them as appropriate to enhance laboratory capabilities.

Qualifications

• BS/MS in Biochemistry, Protein Engineering, or related discipline, with 1-2+ years of biotech/pharma experience
• Industry experience in antibody drug discovery a plus
• Hands-on experience with mammalian cell culture sterile techniques as well as basic biochemical laboratory equipment and techniques (e.g., multichannel pipettors, Nanodrop, SDS-PAGE, CE-SDS, FPLC, plate washers, plate readers, etc)
• Experience working in a fast-paced and highly collaborative team environment
• Excellent oral and written communication skills
• Fluency with GraphPad Prism, Microsoft Excel, Word, and Powerpoint
• Experience with LIMS and/or ELN platforms, such as Benchling or similar
• Experience with liquid handler protocols and programming a plus
• Ability to work across various US and international time zones

Taking Care of Our People
We support the individuality of what people need to do outside of work to empower them to do their best at work. While you focus on making better medicine together, we focus on programs and benefits that support a diverse and growing team. Whether you’re single, in a growing family, or nearing retirement, Alloy offers a variety of comprehensive and competitive benefits starting from day one.
Compensation

• Competitive base and equity compensation commensurate with level of experience and independence
• 401(k) company match

Health & Family

• Generous personal and family medical, dental and vision benefits with 100% of premiums and deductibles covered
• Company-paid disability (STD, LTD) and life insurance
• Paid parental leave
• Family planning support up to $45,000 (e.g., IVF/PGT, adoption, surrogacy, egg retrieval)

Unique Perks

• Unlimited PTO (paid time off) and flexible schedules
• Annual stipend for continuing education with commitment to your career through individualized professional development plan
• Wellness and Extensive Employee Assistance Program (EAP) including resources for mental wellness

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Pay Transparency
At Alloy Therapeutics, we believe in fostering trust and open communication. For this role, the estimated annual base salary range is $63,600 - 68,900, with the final offer based on factors like your experience, skills, and alignment with our needs.

Additionally, this role is eligible for equity compensation, reflecting our commitment to shared success as we work together to make better medicines.

We are proud to offer competitive compensation and benefits, aiming to support our team’s professional and personal well-being. If you have any questions about pay or benefits, we’re here to help.

Alloy Therapeutics is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, sexual orientation, gender identity, veteran status, disability, or other legally protected status. If you are unable to submit an application because of incompatible assistive technology or a disability, please contact us at recruiting@alloytx.com. We will make every effort to respond to your request for disability assistance as soon as possible.

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