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Senior Medical Director - Respiratory Translational Medicine (Early Pipeline Unit)
Senior Medical Director - Respiratory Translational Medicine (Early Pipeline Unit)GSK • Waltham, MA, United States
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Senior Medical Director - Respiratory Translational Medicine (Early Pipeline Unit)

Senior Medical Director - Respiratory Translational Medicine (Early Pipeline Unit)

GSK • Waltham, MA, United States
[job_card.30_days_ago]
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  • [job_card.full_time]
[job_card.job_description]

Overview

Senior Medical Director – Respiratory Translational Medicine role within GSK’s Early Portfolio Unit. The ideal candidate has deep expertise in COPD, with a strong translational research background and demonstrated ability to bridge clinical insights and experimental medicine to accelerate development of novel therapies. The role includes co-leading the COPD Disease Area Acceleration Team and leading matrix teams to translate COPD strategies into patient benefit.

About RIIRU

The Respiratory, Immunology and Inflammation Research Unit (RIIRU) identifies novel targets with human genetic associations to disease and develops assets for clinical studies, performing up to Phase 2 studies. This is enabled through strategic external partnerships and internal collaborations.

Note : The career opportunity requires on-site presence (minimum of two days a week) at one of GSK’s US or UK sites.

Key Responsibilities

Scientific Leadership

  • Provide disease-level leadership to develop causal maps of pathobiology and tools / endpoints / biomarkers to enable timely experimentation and derisk mechanisms and programmes.
  • Lead translational and clinical strategies for COPD programmes in the Early Pipeline Unit, ensuring study designs align with the IEP and CDP, regulatory requirements, product development plan, and commercial goals.
  • Stay current with COPD and related respiratory research, trial methodologies, and regulatory changes to maintain competitive edge.
  • Contribute to regulatory interactions, including briefing documents and responses.
  • Contribute to Business Development activities, including due diligence projects.
  • Champion translational and biomarker strategies across the early respiratory portfolio.

DAAT Leadership

  • Co-lead the COPD Disease Area Acceleration Team (DAAT), aligning scientific and clinical strategies with business objectives through matrix leadership of large cross-functional teams.
  • Evaluate therapeutic potential and clinical tractability of targets within the disease area.
  • Identify transformational opportunities where projects offer significant patient benefits.

    • Program Delivery

  • Ensure quality, on-time, and on-budget delivery of studies and programmes within an therapeutic area of EPU.
  • Design and implement experimental medicine studies.
  • Oversee risk assessment across programs and implement mitigation strategies.

    • Collaboration and Matrix Working

  • Collaborate with cross-functional teams across Advance Pipeline Unit, Commercial, and Research Technologies.
  • Build and maintain networks with internal and external stakeholders, including academic institutions, CROs, and regulators.
  • Represent GSK effectively in external collaborations and negotiations.

    • Problem Solving and Decision Making

  • Anticipate challenges and develop strategies to mitigate risks.
  • Make decisions balancing risk / benefit with clear impact understanding.
  • Written and Oral Communication : Lead writing and review of study-related documents and regulatory submissions; communicate confidently at all levels.
  • Ways of Working : Champion innovative processes to improve clinical development outcomes.

    • What We Offer

    GSK is an Equal Opportunity Employer. The company values a diverse and inclusive workforce and provides opportunities for applicants regardless of race, color, religion, sex, gender identity, sexual orientation, parental status, national origin, age, disability, or genetic information.

    Qualifications

    Basic Qualifications

  • Medical degree with board qualification / registration in Respiratory Medicine or related fields.
  • Experience in global pharmaceutical / biotech industry in respiratory medicine with focus on COPD, biology and potential targets.
  • Industry experience in respiratory / COPD clinical drug development, including translational medicine and early phase development.
  • Experience planning clinical development for assets / indications.
  • Experience working with multiple stakeholders on complex projects and leading cross-functional matrix teams.
  • Experience in translational medicine, clinical research methodology, and biostatistics for innovative trial designs with data-driven decision rules.

    • Preferred Qualifications / Experience

    PhD is highly desirable in addition to medical degree; strong leadership and relationship-building skills; track record of creative problem solving in clinical trials; transferable leadership for coaching and development; strong network of scientific and clinical thought leaders; experience with tech-enabled solutions in biology, translation, or clinical development.

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