Senior Scientist II, Quantitative Bioimaging

Company DescriptionJob Description

AbbVie is seeking an independent and innovative Senior Scientist to join our Imaging group. In this role, you will lead the development and integration of advanced microscopy and quantitative imaging strategies, enabling high-resolution, quantitative analysis of biological responses in both 2D and 3D models such as state-of-the-art organ-on-a-chip platforms. This is a high-impact position that directly advances therapeutic model development, supporting key initiatives in Complex In Vitro Models (CIVM) and aligning with the broader objectives of Immunology discovery programs. The work will span the fields of biology, bioengineering, and computational sciences, so candidates with experience combining two or more of these subjects will be preferred.

Key Responsibilities:

• Proficient in imaging assays and data analysis; strong expertise in high content imaging and phenotypic in vitro assay development, multi-parametric computational image analysis, QC, and data visualization.
• Design, implement, and optimize image acquisition pipelines for 2D and 3D cellular/tissue models using different microscopy platforms.
• Promote the use of novel experimental approaches and adoption of complex in vitro models; routinely investigate/create innovative processes, hypotheses and methodologies.
• Collaborate with cross-functional teams including biologists, pathologists, and bioinformaticians to conceptualize assays, execute experiments, and generate robust data.
• Apply advanced machine learning methods to identify novel biomarkers and correlate results with molecular and phenotypic signatures; integrate data from in vitro models and tissue specimens.
• Proactively monitor new technologies, bringing innovative imaging and analysis solutions to project teams.
• Analyze and interpret data, integrating imaging and functional readouts, and effectively communicate results to internal stakeholders and external collaborators.

Qualifications

Required Qualifications:

• BS, MS, or PhD in Bioengineering, Biology, or a related field, with typically 12+ (BS), 10+ (MS), or 3+ (PhD) years of relevant industry experience.
• Demonstrated expertise in 2D and 3D cell culture models and advanced microscopy.
• Proficient in image analysis tools (e.g., Imaris, ImageJ/Fiji) and programming languages (e.g., Python, MATLAB) for developing custom analyses.
• Strong background in quantitative 3D image analysis, data visualization, and statistical analysis.
• Demonstrated experience integrating and analyzing complex biological datasets.
• Track record of implementing emerging cell biology technologies in 3D and organ-on-a-chip systems.

Preferred Qualifications:

• Experience with organoids, organ-on-chip models and other advanced in vitro model platforms.
• Strong understanding of transport phenomena in biological systems.
• Excellent problem-solving and communication skills, collaborative mindset, and ability to convey complex results to diverse audiences.
• Self-driven and proactive, with the ability to manage multiple priorities, and adapt to evolving objectives in a fast-paced environment.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. ​

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

• This job is eligible to participate in our short-term incentive programs. ​

• This job is eligible to participate in our long-term incentive programs. ​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

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