Summary
• Carry out NGS and epigenomics assays in support of large collaborative initiatives
• Contribute to the development of NGS assays to benefit drug discovery and translational research
• Perform a wide variety of molecular biology techniques with minimal supervision and with an exceptional attention to details
• Generate NGS libraries and perform library QC upstream of sequencing
• Develop and edit protocols and standard operating procedures
• Perform a wide variety of basic molecular biology techniques with minimal supervision
• Maintain an uninterrupted supply of reagents and consumables for ongoing collaborative efforts
• Effectively communicate results in a group setting
• Maintain an accurate and complete laboratory notebook and other records, as needed
Skills/Knowledge preferred
• PhD or MS degree with 3-4+ years of professional experience in molecular biology, biotechnology, or biochemistry
• Demonstrated expertise in molecular biology techniques, including DNA/RNA extraction & purification, NGS library preparation & QC, PCR, qPCR, etc.
• Hands-on experience with epigenomics assays such as chromatin immunoprecipitation (ChIP-seq), DNA methylation assays, or ATAC-seq
• Experience with cell-free nucleic acids (isolation, NGS applications)
• Competence in routine mammalian cell culture and sterile technique
• Strong understanding of NGS technologies, with a track record of utilizing such assays in a research environment
• Familiarity with Illumina sequencing, and hands-on experience in the generation and QC of Illumina sequencing libraries
• Experience with standard molecular biology tools e.g., PCR, qPCR, gel and capillary electrophoresis
• Proficiency with MS Office suite, and ability to understand and present on genomics data
• Strong organizational skills and comfort with systems e.g., Confluence, JIRA, SharePoint systems
• Commitment to quality by rigorous and constant evaluation of own work
• Adaptability; able to function effectively in a fast paced and rapidly changing environment
• Ability to use technical skills and good time management to perform work efficiently and meet project timelines
Additional Responsibilities:
• Play a key role in the utilization of genomics assays across diverse research programs
• Work under the guidance of a principal scientist to reliably generate high quality data to ongoing collaborative research efforts
• Must be a strong team player with a positive attitude and be flexible to changes in project priorities
Research Scientist • San Diego, CA
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