Medical Director

Medical Director

Join Jade Biosciences

About Jade Biosciences

Jade Biosciences is focused on developing innovative, best‑in‑class therapies to address critical unmet needs in autoimmune diseases. Our lead candidate, JADE101, is designed to inhibit the cytokine APRIL (A Proliferation‑Inducing Ligand) and is being developed for the treatment of immunoglobulin A nephropathy (IgAN), a chronic kidney disease that can impair kidney function over time. JADE101 aims to reduce harmful IgA antibodies, lower proteinuria (a key marker of kidney damage), and preserve long‑term kidney function. A Phase 1 healthy‑volunteer study of JADE101 is ongoing, with interim, biomarker‑rich data expected in the first half of 2026. Jade’s pipeline also includes a second development candidate, JADE201, and an undisclosed antibody discovery program, JADE‑003, both currently in preclinical development.

Role Overview

Reporting to the Senior Medical Director, the Medical Director will oversee several studies across Jade programs from a Clinical Development perspective, ensuring study integrity and active collaboration with cross‑functional teams to support successful trial execution. This is a fully remote role and will require occasional travel.

Key Responsibilities

• Lead the design, execution, and oversight of clinical trials and provide leadership to study teams, ensuring effective collaboration and achievement of milestones.
• Serve as a Medical Monitor for clinical trials ranging from Phase 1 to Phase 3 studies, ensuring study integrity and closely tracking safety and efficacy data.
• Analyze, interpret, and report clinical data to drive informed decision‑making.
• Ensure the timely and accurate completion of trial‑related documents, including clinical trial protocols, investigator brochures, medical monitoring plans, site training materials, clinical study reports, regulatory submissions, and SOPs.
• Build and maintain relationships with investigative sites, clinical consultants, and key opinion leaders to advocate for the company’s interests.
• Collaborate with the internal safety team to analyze and report safety data, including SAEs from clinical trials.
• Apply medical expertise and hands‑on clinical experience to ensure the relevance and rigor of the development program.
• Collaborate with cross‑functional teams to optimize product development.
• Continuously maintain the highest level of scientific and clinical expertise in the relevant disease‑specific area.

Qualifications

Position Location

This is a remote role; periodic travel to team and company events is required.

Salary

The anticipated salary range for candidates for this role is $270,000–$300,000. The final salary offered will depend on several factors, which may include, but are not limited to, relevant years of experience, educational background, and geography.

Equal Opportunity Statement

As part of the I‑9 verification of authorization to work in the United States, Jade Bioscience participates in E‑Verify. To learn more about E‑Verify please review this poster.

Jade Biosciences is proud to be an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.

Seniority level

Director

Employment type

Full‑time

Job function

Health Care Provider

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