Talent.com
Translational Bioinformatics Scientist
Translational Bioinformatics ScientistAstellas Pharma Inc. • Cambridge, MA
Translational Bioinformatics Scientist

Translational Bioinformatics Scientist

Astellas Pharma Inc. • Cambridge, MA
[job_card.30_days_ago]
[job_preview.job_type]
  • [job_card.full_time]
[job_card.job_description]

Responsibilities :

  • Collaborate with Global Translational Medicine Leads to design and execute analysis plans that address key translational research questions from asset teams. These may include indication and / or patient selection, biomarker discovery (pharmacodynamic, prognostic, and predictive, and disease biomarkers)
  • Identify and leverage relevant public and proprietary datasets to support translational objectives, and effectively communicate findings and insights to cross-functional asset teams.
  • In alignment with current and future portfolio needs, partner with Global Translational Bioinformatics Leads to develop and implement novel analytical methodologies and platforms, such as spatial transcriptomics workflows and integrated data portals, to enable cutting-edge translational research.
  • Support the ingestion, curation, and archiving of large-scale omics and imaging datasets generated from Astellas-sponsored clinical trials and academic collaborations.

Requirements

Qualifications : Required

  • Ph.D. in computational biology, bioinformatics, or other biomedical sciences with 4-6 years’ experience in applying bioinformatics or computational approaches to drug discovery / development, preferably in a biopharma setting
  • Strong hands-on experience with Python, R, or similar languages commonly used in bioinformatics or image analysis
  • Demonstrated expertise in analyzing multi-omics and clinical data to support research into disease mechanisms, patient stratification and biomarker discovery
  • Experience in at least one of the following domains : advanced spatial transcriptomics analytics (oncology), advanced imaging analytics (oncology), or ophthalmology clinical imaging biomarker analytics
  • Strong problem-solving mindset and willingness to work collaboratively in cross-functional clinical research environments
  • Good communication skills, especially in explaining technical concepts to non-technical stakeholders.
  • Eager to learn new technologies and passion in translational / clinical research

    • Preferred

  • Exposure to deep learning frameworks (e.g., PyTorch, TensorFlow) and experience training or fine-tuning models on oncology imaging (H&E, IHC, mIF, etc) or omics data is a plus
  • Some experience in ophthalmic imaging analysis (OCT, FAF, etc.) is a plus but not required

    • Salary Range

    $130K – $170K (NOTE : Final salary could be more or less, based on experience)

    Benefits :

  • Medical, Dental and Vision Insurance
  • Generous Paid Time Off options, including Vacation, Sick time, plus national holidays including Heritage Days, and Summer and Winter Breaks
  • 401(k) match and annual company contribution
  • Company paid life insurance
  • Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
  • Long Term Incentive Plan for eligible positions
  • Referral bonus program
    • [job_alerts.create_a_job]

    Scientist • Cambridge, MA

    [internal_linking.related_jobs]
    Senior Expert II AI and Computational Sciences

    Senior Expert II AI and Computational Sciences

    Novartis Group Companies • Cambridge, MA, United States
    [job_card.full_time]
    Novartis has embraced a bold strategy to drive a company-wide digital transformation.Our objective is to position Novartis as an industry leader by proactively adopting digital technologies that fo...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Lead Bioinformatics & Data Infrastructure

    Lead Bioinformatics & Data Infrastructure

    Beth Israel Lahey Health • Boston, MA, United States
    [job_card.full_time]
    A healthcare organization in Massachusetts is seeking a Bioinformatician / Data Infrastructure & Analytics Lead to drive its computational strategy and manage data infrastructure.The ideal candidat...[show_more]
    [last_updated.last_updated_variable_hours] • [promoted] • [new]
    Bioinformatician II, Pathology

    Bioinformatician II, Pathology

    Mass General Brigham (Enterprise Services) • Somerville, MA, United States
    [job_card.full_time]
    Drives the application of clinical bioinformatics and other clinical / research / education informatics needs in the department through software engineering. Manage multiple bioinformatics coding tasks ...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Senior Expert II biomedical Machine Learning Innovation Scientist

    Senior Expert II biomedical Machine Learning Innovation Scientist

    Novartis • Cambridge, Massachusetts, United States
    [job_card.full_time]
    This job is with Novartis, an inclusive employer and a member of myGwork – the largest global platform for the LGBTQ+ business community. Please do not contact the recruiter directly.Novartis has em...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Senior Expert II (Scientific Innovation), AI and Computational Sciences (AICS)

    Senior Expert II (Scientific Innovation), AI and Computational Sciences (AICS)

    Novartis Group Companies • Cambridge, MA, United States
    [job_card.full_time]
    Novartis has embraced a bold strategy to drive a company-wide digital transformation.Our objective is to position Novartis as an industry leader by proactively adopting digital technologies that fo...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Bioinformatics Associate — TB Genomics and Phenotype Link

    Bioinformatics Associate — TB Genomics and Phenotype Link

    Harvard University • Boston, MA, United States
    [job_card.full_time]
    A prestigious academic institution in Boston is looking for an Associate in Biomedical Informatics.The role involves conducting bioinformatic analysis and researching correlations in treatment outc...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    ProFound Therapeutics, Inc. | Boston, MA Senior / Principal Scientist, Biostatistics & Computatio[...]

    ProFound Therapeutics, Inc. | Boston, MA Senior / Principal Scientist, Biostatistics & Computatio[...]

    Flagship Pioneering • Boston, MA, United States
    [job_card.full_time]
    Senior / Principal Scientist, Biostatistics & Computational Biology.ProFound Therapeutics is seeking a pioneering.Senior Scientist / Principal Scientist, Biostatistics & Computational Biology.ProFoundr...[show_more]
    [last_updated.last_updated_30] • [promoted]
    Hybrid VP, Translational Research — Rare Disease & Metabolism

    Hybrid VP, Translational Research — Rare Disease & Metabolism

    Rhythm Pharmaceuticals, Inc • Boston, MA, United States
    [job_card.full_time]
    A leading biopharmaceutical company in Boston seeks a Vice President of Translational Research.The successful candidate will lead strategic initiatives across non-clinical development, focusing on ...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Senior Scientist, Translational Research - Real World Data Science

    Senior Scientist, Translational Research - Real World Data Science

    Tempus, Inc. • Boston, MA, United States
    [job_card.full_time]
    Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world...[show_more]
    [last_updated.last_updated_30] • [promoted]
    Computational Biology / Bioinformatics / Machine Learning Postdoc - Single Cell and Spatial Technolo

    Computational Biology / Bioinformatics / Machine Learning Postdoc - Single Cell and Spatial Technolo

    Beth Israel Deaconess Medical Center • Boston, MA, US
    [job_card.full_time]
    The Vlachos Lab and the Spatial Technologies Unit (www.AI / ML and computational biology methods.The researcher will have the ability to leverage. Available projects revolve around cancer immunology, ...[show_more]
    [last_updated.last_updated_30] • [promoted]
    Bioinformaticist I

    Bioinformaticist I

    Harvard University • Boston, MA, United States
    [job_card.temporary]
    By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expert...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Senior Scientist, Translational Research - Real World Data Science

    Senior Scientist, Translational Research - Real World Data Science

    Tempus AI • Boston, MA, US
    [job_card.full_time]
    Senior Scientist, Translational Research - Real World Data Science Join to apply for the Senior Scientist, Translational Research - Real World Data Science role at Tempus AI.Passionate about pre...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Senior Expert II (Biomedical AI Methods Expert

    Senior Expert II (Biomedical AI Methods Expert

    Novartis • Cambridge, Massachusetts, United States
    [job_card.full_time]
    This job is with Novartis, an inclusive employer and a member of myGwork – the largest global platform for the LGBTQ+ business community. Please do not contact the recruiter directly.Novartis has em...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Senior Associate Scientist, Bioinformatics

    Senior Associate Scientist, Bioinformatics

    Alnylam Pharmaceuticals • Cambridge, MA, United States
    [job_card.full_time]
    With six commercially approved RNAi therapeutics, Alnylam is at the forefront of gene silencing.Our success is built upon a rational, sequence-based approach to drug design driven by predictive mod...[show_more]
    [last_updated.last_updated_30] • [promoted]
    Computational Biologist : Drug-Seq & AI-Driven MoA Insights

    Computational Biologist : Drug-Seq & AI-Driven MoA Insights

    Ginkgo Bioworks Inc. • Boston, MA, United States
    [job_card.full_time]
    A leading biotech firm is seeking a Data Analyst to join their Functional Genomics team in Boston, MA.The role focuses on analyzing Drug-seq data and building reproducible analysis pipelines to der...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Computational Biology Intern

    Computational Biology Intern

    Massachusetts Eye and Ear • Boston, MA, United States
    [job_card.full_time]
    Bioinformatics Student Researcher (Single-Cell Biology).We are seeking a motivated student with emerging interest in computational biology to join our research group and contribute to single-cell t...[show_more]
    [last_updated.last_updated_variable_days] • [promoted]
    Senior AI Scientist, Observability Platform

    Senior AI Scientist, Observability Platform

    Datadog • Boston, MA, US
    [job_card.full_time]
    A leading SaaS company is seeking a Senior Applied Scientist for their Observability Data Platform.The ideal candidate will leverage expertise in areas like causal modeling and reinforcement learni...[show_more]
    [last_updated.last_updated_variable_hours] • [promoted] • [new]
    Bioinformatician

    Bioinformatician

    Zifo • Cambridge, MA, US
    [job_card.full_time]
    [filters_job_card.quick_apply]
    This role will require regular (~3 days / week) presence on-site at the client in Cambridge, MA • •.This role is not eligible for relocation assistance • •. This role is also open to candidates on a con...[show_more]
    [last_updated.last_updated_variable_days]