Postdoctoral Researcher (C. elegans Neural Activity Imaging and Experimentation)

Role : Postdoctoral Researcher (C. elegans Neural Activity Imaging)

Location : San Francisco, CA, USA (On-site)

Start Date : ASAP

Duration : Initial appointment is for 1 year, with extensions (up to a total of 3 years) contingent upon performance

Announcement

We are inviting applications for a Postdoctoral Researcher position focused on neural activity imaging and behavioral analysis of C. elegans. This role is central to a multi-phase program aiming to record and model neural circuit dynamics with unprecedented fidelity, combining advanced optical microscopy, neural circuit inference, and machine learning.

About

Episteme is a new type of R&D company based in San Francisco. We identify, hire, and bring together exceptional scientific researchers across disciplines and geographies-especially individuals who want to pursue difficult and important problems that do not fit into the purview of traditional institutions. Our aim is to create a new path separate from academia, industry, and government for enabling, translating, and commercializing science into tangible impact.

Overview

As a Postdoctoral Researcher, you will design and lead experiments that record large-scale neural activity from C. elegans using advanced optical imaging approaches. You will work closely with collaborators in optics, microfluidics, and machine learning to produce high-quality neural activity and behavior datasets that drive the development of circuit-level models. This role is ideal for individuals with strong experimental training in C. elegans behavioral neuroscience, activity imaging and an interest in connecting data to theory.

Research Focus Areas

• Whole-brain and population-level activity imaging in C. elegans (e.g. calcium or voltage indicators)
• Advanced optical microscopy methods for high-throughput, stable recording of small organisms
• Neural circuit analysis linking activity patterns to behavior, stimuli, and sensory / motor function
• Integration of imaging with computational models of neural dynamics

Key Responsibilities

Qualifications

Application Instructions

To apply, please upload the following materials along with your application in Ashby :

We strongly encourage early submissions. Positions will remain open until filled. For questions, please contact Dr. Michael Skuhersky at recruiting@episteme.com.

Additional Information

In addition to competitive salaries, Episteme offers a comprehensive benefits package. You will be part of a collaborative effort bridging neuroscience, machine learning, and advanced imaging, with opportunities for high-impact publications and career advancement.