Clinical/Development - Lab Automation Engineer

Job Title: Lab Automation Engineer
Location: Cambridge, MA
Duration: 9 Months

Job Summary
Summary of Key Responsibilities

• We seek a passionate, experienced, and creative Lab Automation Scientist or Engineer to drive the implementation of automated and robotic solutions across our drug discovery platform.
• The candidate will become an integral member of a multidisciplinary team advancing Client RNAi therapeutic programs from target discovery through drug candidate lead selection.
• The primary objectives of the team are to develop highly scalable screening platforms and protocols to continually increase both throughput and decision-enabling content.
• The successful candidate will implement high-throughput workflows incorporating liquid- and plate-handling robotics in support of diverse application areas, including in vitro screening, ex-vivo sample processing, and high-throughput RNA-seq, including transcriptional profiling, spatial and single-cell applications.

Key Responsibilities:

• Optimize, troubleshoot, and stabilize ex vivo sample-processing methods on the HighRes platform.
• Collaborate with cross-functional scientists to streamline ex vivo sample-processing workflows.
• Onboard and develop automated methods on the new PE JANUS and Beckman liquid-handling systems.
• Lead the transition of two manual workflows to robotic liquid-handling platforms.
• Perform maintenance and troubleshooting for the integrated HighRes system and associated processes.
• Serve as a liaison between external vendors and cross-functional site stakeholders.
• Train users and provide ongoing support for existing robotic platforms.

Qualifications:

• B.S. or M.S. degree in Bioengineering, Engineering, Biochemistry, Molecular Biology, or related field
• 5 years of hands-on experience operating and programming robotics platforms.
• Ability to understand diverse and complex workflows on liquid- and plate- handling systems, including the sources and statistical assessment of unwarranted assay variance
• Experience with liquid handlers and integrated platform such as PerkinElmer, HighRes Cellario, and Beckman Coulter.

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