Bioinformatician II - Psychiatry

Job Description

The Center for Disease Neurogenomics (CDN) at the Icahn School of Medicine at Mount Sinai is seeking a proactive and detail-oriented Bioinformatician II to join a multidisciplinary team supporting the analysis, infrastructure, and data stewardship of large-scale functional genomics datasets. This position is intended for candidates with practical experience managing omics data, maintaining computational infrastructure, and developing efficient solutions to support high-throughput data processing and secure storage.

Qualifications

• M.S. in Bioinformatics, Biomedical Informatics, Computational Biology, or Genomics. Alternately, M.S. in a discipline requiring strong computational and analytical skills supplemented with some biology exposure. Ph.D in a related field preferred. Those with a Bachelors degree and additional post-graduate experience are considered.

• 2+ years post-graduate experience in a research environment, including the manipulation of large biological datasets.; with =3 years of experience preferred

• Advanced knowledge of genetics and/or statistical analysis software and online resources. Experience in programming environments such as MatLab, R statistical package, BioConductor, Perl and C++.

• Proficiency in Python and R; working knowledge of SQL and Linux shell scripting.

• Experience processing large-scale omics data (RNA-seq, ATAC-seq, or WGS).

• Experience using or developing Nextflow or Snakemake-based pipelines is a strong plus.

• Strong problem-solving skills, ability to prioritize, and attention to reproducibility and data integrity.

• Preferred Qualifications:

• Demonstrated experience maintaining or developing data tracking systems or LIMS solutions.

• Familiarity with HPC environments and workload managers (e.g., LSF, SLURM).

• Experience with cloud-based genomics analysis platforms such as CAVATICA, Verily Workbench, Google Cloud Platform (GCP), Amazon Web Services (AWS), or comparable environments.

• Experience with data privacy standards and compliance in biomedical datasets.

Responsibilities

• Assist in the preprocessing, demultiplexing, and quality control of single-cell and bulk sequencing data across multiple assays (RNA-seq, ATAC-seq, multiome).

• Implement and maintain metadata infrastructure for tracking donor/sample provenance and cohort selection across projects using a relational database backend.

• Monitor and maintain local high-performance computing resources, including scripting of automated usage summaries, quota alerts, and issue tracking.

• Support data transfers, pipeline execution, and user coordination in hybrid cloud environments (e.g., CAVATICA, GCP).

• Write and maintain robust, well-documented code (e.g., Snakemake, bash, R, Python) for processing and managing large-scale datasets.

• Respond to infrastructure incidents (e.g., disk quota overflows, data loss risks) and proactively implement safeguards.

• Contribute to documentation and training materials to enable team-wide system usage.

• Other related duties as assigned.

About Us

Strength through Unity and Inclusion

The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai's unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual.

At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well-being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to building a supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally. Explore this opportunity and be part of the next chapter in our history.

About the Mount Sinai Health System:

Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time - discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients' medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report's "Best Children's Hospitals" ranks Mount Sinai Kravis Children's Hospital among the country's best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek's "The World's Best Smart Hospitals" ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.

Equal Opportunity Employer

The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization.

Compensation Statement

Mount Sinai Health System (MSHS) provides a salary range to comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $65885 - $100000 Annually. Actual salaries depend on a variety of factors, including experience, education, and hospital need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.