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Machine learning engineer Jobs in San Mateo, CA

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Machine learning engineer • san mateo ca

Last updated: 2 days ago

Associate Director/Principal, Machine Learning Scientist

BigHat BiosciencesSan Mateo, California, US
Full-time
Quick Apply

We are seeking a creative, accomplished Assoc.Director or Principal Machine Learning Scientist to advance the state of the art in ML-driven therapeutic antibody design.At BigHat Biosciences our ful...Show more

Machine Learning Engineer

Intelliswift Software IncCA - South San Francisco
Full-time

Work closely with AI and imaging scientists in machine learning work streams including but not limited to semantic segmentation, object detection and classification.Work closely with Client and dat...Show more

CNC Lathe / Swiss Screw Machine Programmer

Ryzen SolutionsRedwood City, CA, US
Permanent
Quick Apply

CNC Lathe/Swiss Screw machine and can set-up and program.Responsibilities:The job responsibilities include but are not limited to the following:.Program- setup and run machine jobs per standard met...Show more

Senior Data Scientist - Ecosystem and Learning Platform

RobloxSan Mateo, CA, United States
Full-time

Senior Data Scientist - Ecosystem and Learning Platform.San Mateo, CA, United StatesData Science & Analytics ID: 5633.Every day, tens of millions of people come to Roblox to explore, create, play, ...Show more

Data Scientist/Machine Learning Engineer

CATHEXISRedwood City, CA, US
Full-time
Quick Apply

Team CATHEXIS elevates the government contracting experience through rapid response, deep skill, and thoughtful problem-solving and communication.Our core capabilities are our top-tier program and ...Show more

Principal Machine Learning Engineer, Embodied AI and Smart NPCs

RobloxSan Mateo, CA, United States
Full-time

Principal Machine Learning Engineer, Embodied AI and Smart NPCs.San Mateo, CA, United StatesEngineeringID: 5898.Every day, tens of millions of people come to Roblox to explore, create, play, learn,...Show more

Remote FTE: Network Engineer (with Programming) – Data & AI Systems - AI Trainer ($50-$70 per hour)

MercorSan Mateo, California, US
Remote
Full-time

Are you a network engineer who also enjoys scripting or programming—and is curious about how data powers intelligent systems? Our client is building vertically integrated networking systems and lev...Show more

Remote Personal Learning / Career Expert - AI Trainer ($55-$75 per hour)

MercorRedwood City, California, US
Remote
Part-time

What you'll do** Mercor is partnering with leading AI labs to advance frontier agent evaluations in career and learning.As a Personal Learning & Career Expert, you'll build long-horizon career and ...Show more

Senior Engineer, Machine Learning

SyntiantRedwood City, CA, US
Full-time
Quick Apply

AI software and semiconductor solutions space, is looking for an experienced and talented.Senior Engineer, Machine Learning.Machine Learning function in a growing organization.Senior Engineer, Mach...Show more

Senior Scientist, Machine Learning (Biologics Design)

Gilead Sciences, Inc.Foster City, California, United States
Full-time

Gilead’s Research Data Sciences is seeking a .This role sits at the intersection of machine learning, structural biophysics, and protein therapeutics, with direct impact on lead optimization and pi...Show more

Senior Scientist I (Machine Learning) - Biologics Drug Substance Development, Cell Culture Development

AbbVieSouth San Francisco, California, United States
Full-time

The Biologics CMC Development team at AbbVie has a long and rich history of biologics development.Now located in a new state of the art facility in South San Francisco, the team leverages its compr...Show more

Machine Learning Engineer/Senior Machine Learning Engineer - Devops

Genentech, IncSouth San Francisco
Full-time

It’s what drives us to innovate.To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come.Creating a world where we all have more ...Show more

Deep Learning Compiler Engineer

quadric, IncBurlingame, CA, US
Full-time
Quick Apply

Quadric has created an innovative general purpose neural processing unit (GPNPU) architecture.Quadric's co-optimized software and hardware is targeted to run neural network (NN) inference workloads...Show more

Learning Support Tutor

Tutor Me EducationRedwood City, CA, US
Part-time
Quick Apply

At Tutor Me Education, we are revolutionizing the way students learn, and we're seeking passionate teachers and tutors with.If you're committed to making a difference in the lives of students with ...Show more

Learning & Development Program Manager - Global Security Services

Pinkerton Consulting & Investigations, Inc.Foster City, US
Full-time

Overview 170+ Years Strong.At Pinkerton, the mission is to protect our clients.To do this, we provide enterprise risk management services and programs specifically designed for each client.Pinkerto...Show more

Remote Machine Learning Engineer Talent Network - AI Trainer ($70-$250 per hour)

MercorSan Mateo, California, US
Remote
Part-time

About Mercor’s talent network** Join our Machine Learning Engineer Expert Network to connect with leading AI labs and companies seeking your expertise.This is an open application for future contrac...Show more

Remote FTE: Network Engineer (with Programming) – Data & AI Systems - AI Trainer ($50-$70 per hour)

MercorSan Bruno, California, US
Remote
Full-time

Are you a network engineer who also enjoys scripting or programming—and is curious about how data powers intelligent systems? Our client is building vertically integrated networking systems and lev...Show more

Remote Machine Learning Engineer Talent Network - AI Trainer ($70-$250 per hour)

MercorSouth San Francisco, California, US
Remote
Part-time

About Mercor’s talent network** Join our Machine Learning Engineer Expert Network to connect with leading AI labs and companies seeking your expertise.This is an open application for future contrac...Show more

Machine Operator

CPP IndustriesBurlingame, CA, United States
Full-time

Now Hiring Machine Operators and Production Workers!.Are you looking to contribute to a large, productive team? Our plastics thermoforming team is now seeking Machine Operators, Quality Inspectors,...Show more

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Associate Director/Principal, Machine Learning Scientist

Associate Director/Principal, Machine Learning Scientist

BigHat BiosciencesSan Mateo, California, US
30+ days ago
Job type
  • Full-time
  • Quick Apply
Job description

Description

The role: We are seeking a creative, accomplished Assoc. Director or Principal Machine Learning Scientist to advance the state of the art in ML-driven therapeutic antibody design.

At BigHat Biosciences our full-stack antibody drug development platform uses ML to drive every stage from discovery to optimization. Our roboticized high-throughput wet-lab continually adds to our large proprietary datasets, which are piped through a custom LIMS++ data management and orchestration layer to automatically update and deploy the latest models. This makes the development of complex, next-gen therapeutics ‘trivially parallelizable’, at a pace which only accelerates as we develop better ML tooling.

You’re not interested in just git-cloning the latest NeurIPS pub and swapping out the dataset. Motivated by an enthusiasm for the possibility of addressing unmet patient needs and a curiosity about the underlying biology, you’ll apply your world-class ML skillset to refine and expand this state-of-the-art protein engineering platform. Success will mean not only hands-on methods development, but helping shape the direction for future ML research, and actively participating in the application of our platform to the accelerated design of new therapeutics.

Key Responsibilities

  • Design and implement the next state-of-the-art generative models of antibody sequence and structure, and predictive models of antibody properties, trained on proprietary internal datasets of thousands to millions of antibodies.
  • Provide leadership, technical guidance, and mentorship to other ML and data science FTEs and interns.
  • Help set strategy for future ML research, driven by a strong high-level understanding of BigHat programs and operations as well as real-world drug development challenges.
  • Develop, refine, and deploy de novo design methods for generating initial hits to challenging, therapeutically interesting targets.
  • Develop multi-modality, multi-objective iterative protein sequence optimization approaches to lab-in-the-loop antibody design problems for validation and deployment in our high-throughput wet lab - at BigHat success is only declared upon synthesis of real antibodies with drug-like properties.
  • Maintain an in-depth understanding of the current state-of-the-art in ML-driven protein engineering, both in the literature and at BigHat.
  • Share your findings at top-tier conferences and publish in leading scientific journals to advance the field of protein engineering.
  • Provide ML expertise and support for ongoing therapeutics programs, directly contributing to the development of new drugs.
  • Collaborate with our engineering team to ensure maximal efficiency in the automated and agentic deployment of our latest models to our therapeutics programs.
  • Work closely with an interdisciplinary team of drug developers, wet lab scientists, automation specialists, data scientists, etc. to identify inefficiencies or potential improvements in BigHat’s platform, and plan and prioritize ML methods development accordingly.

Skills Knowledge and Expertise

  • PhD in ML/CS or in the hard sciences with 5+ years experience post-graduation in developing and applying novel ML methods, and a strong quantitative background.
  • Publications in major ML conferences and/or leading journals, and an extensive demonstrable track record developing and applying novel ML in industry.
  • Strong competency in Python, familiarity with PyTorch, and experience with modern software engineering best practices.
  • Excellent communication skills, sufficient biomedical domain knowledge to interact effectively with diverse scientific teams.
  • Enjoys a fast-paced environment and excels at executing across multiple projects.
  • Familiarity with the current state-of-the-art in ML-driven protein engineering
  • Nice-to-haves include experience with de novo design, NGS data, Bayesian optimization, familiarity with antibody biology and drug development, and experience training and deploying models on AWS.

Total Rewards

The salary estimated for this position is $254,000 - $290,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.

What BigHat Offers:
  • Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived)
  • Dental, and vision coverage through Guardian
  • Additional well-being benefits through Nayya, OneMedical, Wagmo, Rula, and more
  • 401(k) with company match
  • DTO, two weeks of company-wide shutdown, and 12 company holidays
  • Paid parental leave
BigHat Biosciences designs safer, more effective biologic therapies for patients using machine learning and synthetic biology.

BigHat integrates a wet lab for high-speed characterization with machine learning technologies to guide the search for better antibodies. We apply these design capabilities to develop new generations of safer and more effective treatments for patients suffering from today’s most challenging diseases.

BigHat is a Series B biotech outside San Francisco with a team-oriented, inclusive, and family-friendly culture. Our broad pipeline of wholly-owned and partnered therapeutic programs span many disparate indications with high unmet need, such as cancer, inflammation, and infectious disease. BigHat has raised >$100M from top investors, including Section 32, a16z, and 8VC.