Postdoctoral Associate

G/R03841P

Postdoctoral Associate

Franklin-Biochemistry

Chartered by the state of Georgia in 1785, the University of Georgia is the birthplace of public higher education in America and is the state’s flagship university (https://www.uga.edu/). The proof is in our more than 240 years of academic and professional achievements and our continual commitment to higher education. UGA is currently ranked among the top 20 public universities in U.S. News & World Report. The University’s main campus is located in Athens, approximately 65 miles northeast of Atlanta, with extended campuses in Atlanta, Griffin, Gwinnett, and Tifton. UGA employs approximately 3,100 faculty and more than 7,700 full-time staff. The University’s enrollment exceeds 41,000 students including over 31,000 undergraduates and over 10,000 graduate and professional students. Academic programs reside in 19 schools and colleges, including our newly established School of Medicine.

Will need evidence of degrees, curriculum vitae, and official transcripts

www.bmb.uga.edu

Employee

11/01/2019

07/03/2019

Yes

Athens Area

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Additionally, USG supports Freedom of Expression as stated in Board Policy 06.05 Freedom of Expression and Academic Freedom.

Isolate Fc gamma receptors from primary human cells

20

Characterize Fc gamma receptors from primary human cells using mass spectrometry

20

Develop a recombinant in vitro model system to express appropriately modified Fc gamma receptors

40

Scientific writing of manuscripts, reports and grants

20

Post-Doctoral Associate AD

Exempt

1.00

A person in this position will have two primary objectives: the first is to purify proteins from peripheral human blood and characterization using mass spectrometry. The second goal is to develop an in vitro expression system to test how protein modifications impact cell activation. The goal of these studies is to determine how cells in the human immune system modify antibody-binding receptors and define how these modifications impact cell activation.

This project is funded by the National Institutes of Health. The goal of this research is to characterize how a specific group of proteins, the Fc gamma receptors, are modified in the human body. Our laboratory has developed protocols to isolate proteins from primary human monocytes and natural killer cells that were isolated from apheresis and through negative selection. We have also determined that modification of the Fc gamma receptors affects antibody binding affinity in vitro. The goal of this position is to determine if receptor modifications impact cell activation.

A Ph.D. in Chemistry, Biochemistry, Cell Biology or a related field.
Preferred Qualifications:
A preferred candidate will have significant experience purifying proteins or experience using mammallian cells. An ideal candidate will have significant experience in both aspects of this position. Experience with mass spectrometry is also valuable, but not required.

Be able to create, test and then teach complex written molecular biology or biochemical protocols. Have excellent sterile technique. Be proficient with primer design, various forms of PCR, DNA/RNA-purification, gel electrophoresis and sequencing. Must be able to transform, overexpress and purify proteins from a host organisms. Excellent record keeping and organizational skills. Must be able to prepare scientific manuscripts and oral presentations. Must be able to work as a team-member and team-lead.

Perform biochemistry experiments in a laboratory. This includes working at a laboratory bench and desk, reaching into equipment including incubators as well as transferring reagents to other rooms.

No

No

No

No

No

Offers of employment are contingent upon completion of a background investigation including, a criminal background check demonstrating your eligibility for employment with the University of Georgia; confirmation of the credentials and employment history reflected in your application materials (including reference checks) as they relate to the job-based requirements of the position applied for; and, if applicable, a satisfactory credit check. You may also be subject to a pre-employment drug test for positions with high-risk responsibilities, if applicable. Please visit the UGA Background Check website.