Research Scientist

Summary

• Carry out NGS and epigenomics assays in support of large collaborative initiatives

• Contribute to the development of NGS assays to benefit drug discovery and translational research

• Perform a wide variety of molecular biology techniques with minimal supervision and with an exceptional attention to details

• Generate NGS libraries and perform library QC upstream of sequencing

• Develop and edit protocols and standard operating procedures

• Perform a wide variety of basic molecular biology techniques with minimal supervision

• Maintain an uninterrupted supply of reagents and consumables for ongoing collaborative efforts

• Effectively communicate results in a group setting

• Maintain an accurate and complete laboratory notebook and other records, as needed

Skills/Knowledge preferred

• PhD or MS degree with 3-4+ years of professional experience in molecular biology, biotechnology, or biochemistry

• Demonstrated expertise in molecular biology techniques, including DNA/RNA extraction & purification, NGS library preparation & QC, PCR, qPCR, etc.

• Hands-on experience with epigenomics assays such as chromatin immunoprecipitation (ChIP-seq), DNA methylation assays, or ATAC-seq

• Experience with cell-free nucleic acids (isolation, NGS applications)

• Competence in routine mammalian cell culture and sterile technique

• Strong understanding of NGS technologies, with a track record of utilizing such assays in a research environment

• Familiarity with Illumina sequencing, and hands-on experience in the generation and QC of Illumina sequencing libraries

• Experience with standard molecular biology tools e.g., PCR, qPCR, gel and capillary electrophoresis

• Proficiency with MS Office suite, and ability to understand and present on genomics data

• Strong organizational skills and comfort with systems e.g., Confluence, JIRA, SharePoint systems

• Commitment to quality by rigorous and constant evaluation of own work

• Adaptability; able to function effectively in a fast paced and rapidly changing environment

• Ability to use technical skills and good time management to perform work efficiently and meet project timelines

Additional Responsibilities:

• Play a key role in the utilization of genomics assays across diverse research programs

• Work under the guidance of a principal scientist to reliably generate high quality data to ongoing collaborative research efforts

• Must be a strong team player with a positive attitude and be flexible to changes in project priorities