Director, Engineering

Director, Engineering

Location: Durham, NC, US Company: oxfordbiom

Join Us in Changing Lives At OXB, our people are at the heart of everything we do. We're on a mission to enable life-changing therapies to reach patients around the worldand we're looking for passionate individuals who embody our core values every day: Responsible, Responsive, Resilient, and Respectful. Following the expansion of our US footprint with the acquisition of a new commercial-scale viral vector facility in Durham, North Carolina we have some new opportunities to join us. We are recruiting a Director, Engineering to join the Durham Leadership Team. In this role you will be lead engineering across Validation, Automation, and Process Engineering, ensuring reliable, compliant, and scalable manufacturing operations, playing a key role in advancing our mission and making a meaningful impact.

Your responsibilities in this role would be:

• Lead and develop a high-performing Engineering function across Validation, Automation, Process Engineering, and Engineering Operations.
• Own end-to-end engineering execution, including CQV, automation systems, process engineering, and equipment lifecycle management.
• Deliver capital engineering programmes (facility upgrades, installations, and expansion) on time, within scope, and on budget.
• Drive engineering strategy and performance to enhance manufacturing reliability, efficiency, compliance, and capacity.
• Ensure robust validation and automation frameworks, supporting cGMP compliance, data integrity, and inspection readiness.
• Partner cross-functionally to support manufacturing, technical transfer, and scale-up, enabling operational readiness and site growth.

We are looking for:

• Bachelor's degree in Engineering, Chemical Engineering, Mechanical Engineering, Electrical Engineering, Bioprocess Engineering, or related technical discipline required; advanced degree preferred.
• Extensive leadership experience (15+ years) in biopharma, biologics, or advanced manufacturing environments.
• Proven leadership across Validation, Automation, and Process Engineering, with experience building and leading high-performing teams.
• Strong cGMP expertise, including regulatory inspection readiness and compliance within biologics or advanced therapy manufacturing.
• Deep technical knowledge of CQV and engineering systems, including lifecycle validation, equipment qualification, and compliance programmes.
• Hands-on experience with automation and manufacturing technologies, such as PLC/SCADA, process controls, and digital manufacturing systems.
• Track record of delivering capital projects and supporting scale-up, technical transfer, and operational readiness within complex or high-growth environments.

About Us: OXB is a quality and innovation-led viral vector CDMO with a mission to enable its clients to deliver life changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, we have more than 30 years of experience in viral vectors; the driving force behind the majority of gene therapies. OXB collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. OXB's world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods, and depth of regulatory expertise.

Why Join Us? Competitive total reward packages Wellbeing programs that support your mental and physical health Career development opportunities to help you grow and thrive Supportive, inclusive, and collaborative culture State-of-the-art labs and manufacturing facilities A company that lives its values: Responsible, Responsive, Resilient, Respect

We want you to feel inspired every day. At OXB, we're future-focused and growing fast. We succeed togetherthrough passion, commitment, and teamwork. Ready to Make a Difference?