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Manus Bio
Pilot Plant Fermentation OperatorManus Bio • Augusta, GA
Pilot Plant Fermentation Operator

Pilot Plant Fermentation Operator

Manus Bio • Augusta, GA
14 days ago
Job type
  • Full-time
Job description

Why work at

Manus Bio:

  • Opportunity – For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.
  • Accountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
  • Passion – We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that come with working on the cutting edge.

Responsibilities:

Interface with process development team to provide resources to solve fermentation and product isolation challenges. Execute and help evaluate experiments. This activity includes:

  • Perform downstream purification operations including centrifugation, chromatography (e.g., affinity, ion exchange), filtration (TFF, depth, sterile).
  • Set up, operate, and clean process equipment such as columns, tanks, and filtration systems.
  • Collect, label, and process in-process and final product samples.
  • Monitor process parameters, record data, and ensure batch documentation is completed accurately.
  • Perform cleaning and sterilization of equipment and cleanroom areas (CIP/SIP procedures).
  • Assist in deviation investigations and continuous improvement initiatives.
  • Collaborate with upstream and quality departments to ensure efficient process flow and product quality.
  • Maintain inventory of DSP consumables and request resupply as needed.
  • Become familiar with all required batch records, execute according to the batch records and ensure clear communication of the targeted design parameters.
  • Execute day-to-day Pilot Plant activities, coordinating equipment maintenance and installation activities, troubleshooting process upsets, troubleshooting equipment and instrumentation problems, optimizing operations, addressing contamination issues, addressing downtime or other runtime losses.
  • Maintain the upkeep of the Pilot Plant equipment through the process of initiating work notifications/work orders and maintenance scheduling; Be capable of correcting minor maintenance issues.
  • Adhere to company environmental, safety, and health policies and procedure. Ensure Pilot Plant compliance with safety and environmental regulations.
  • Physical demand requirements are more than sedentary work due to inspection of equipment. Must be able to climb stairs and ladders. Must be able to lift 50 pounds.
  • Must be able to wear the required protective equipment, including respirators when needed.
  • Work schedule is considered shift but will vary depending on manufacturing plan and other extraordinary conditions.

Required Qualifications:

  • High school diploma or GED equivalent.
  • Minimum of 3 years downstream or related plant operator experience.
  • Must be able to follow minimal instructions and support safe work practices.
  • Must be an excellent team member with strong communication skills and a desire to work collaboratively.
  • Must be flexible with day-to-day duties and able to thrive in a start-up environment.
  • Must hold themselves to the highest professional and ethical standards.
  • Some familiarity with the production fermentation and downstream processes and equipment as well as microbiological and analytical laboratory procedures.
  • Demonstrates flexibility in job rotations/various assignments.
  • Basic PC skills which include Windows, Microsoft Office.

Preferred Qualification and Working Style:

  • SAP skills
  • Certified Train the Trainer skills
  • Delta V controls experience

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Pilot Plant Fermentation Operator • Augusta, GA

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