Fulcrum Neuroscience is a biotech startup developing new therapeutic approaches to Alzheimer's disease and other neurodegenerative conditions. At the heart of Fulcrum's approach is a unique computational platform: the Brain Health and Neurodegeneration world model, reconciling over 1,800 literature and data sources, and an underlying AI-enabled, digital twin computational engine. This platform enables Fulcrum scientists to explore target and therapeutic alternatives, identify biomarker patterns, and design lab and clinical experiments.
Fulcrum is establishing collaborations with leading research institutions and pharmaceutical organizations, and is a member of the Global Neurodegeneration Proteomics Consortium (GNPC), enabling access to the GNPC data sets. The Fulcrum software platform supports expansion through plug-ins and APIs, enabling integration with a wide range of AI and analysis tools and data sources.
Reporting to the Chief Technology Officer, you support the development of AI-driven tools to enable the development and enhancement of biological models, digital populations, digital twins, and model-enabled research. This is a hands-on role, working closely with proven innovators in the development of new modeling methodologies and technology.
Your work will include:
This is an opportunity to work at the ground level of an early-stage startup, contributing to leading-edge research on neurodegenerative disease while working at the leading edge of AI-infused scientific tooling.
The ideal candidate would be based in the San Francisco Bay Area and able to work at the company's office in South San Francisco, CA one day per week. Remote candidates with a willingness to periodically travel to South San Francisco will be considered.
Required
Highly Desired
This is a full-time, contract-to-hire role: we intend it as a path to full-time employment.
Direct applicants only, please. We are not working with staffing agencies or third-party recruiters for this contract opportunity and are not accepting agency-submitted candidates.
Sr. Software Engineer (Contract-to-Hire) • South San Francisco, California, United States
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